前列腺胚胎性横纹肌肉瘤1例报告并文献复习

目的探讨前列腺胚胎性横纹肌肉瘤的诊治方法。方法分析1例前列腺胚胎性横纹肌肉瘤患者的临床资料,并结合文献进行复习。结果患者在前列腺根治性切除术后行异环磷酰胺、阿霉素化疗加用泌尿系统保护剂美司那。术后1年发现膀胱转移瘤,施行膀胱根治性切除术,随访15个月未见病灶复发或扩散,患者无瘤存活。结论前列腺胚胎性横纹肌肉瘤CT检查表现为软组织肿块,密度近似于正常肌肉,仅能提示前列腺稍大,对早期诊断价值不大,需经病理检查才能确诊。治疗以根治性手术为主,辅以化疔。我们采用异环磷酰胺、阿霉素化疗加关司那疗效较好,值得临床进一步证实。     

腹膜后多形性横纹肌肉瘤1例

正患者男,60岁,因"左腰部肿块进行性增大1个月"入院。查体腰部无压痛,实验室检查无异常。CT:巨大软组织肿块位于左侧腹膜后(12.2cm×11.0cm×12.5cm)及腹腔内(8.2cm×7.4cm×9.8cm);MRI:平扫T1WI肿块呈等-稍低信号(图1A),T2WI呈不均匀明显高信号(图1B),内可见囊变、坏死,未见出血;增强扫描肿块呈持续填充式强化,其内可见无强化区域(图1C)。影像学诊断:腹膜后平滑肌肉瘤。行开     

Metastatic cutaneous breast carcinoma: A case report and review of the literature

Cutaneous metastatic carcinoma, also known as carcinoma erysipeloides, is an unusual clinical finding. In women, it is most frequently found in association with breast cancer rather than other visceral malignancies. Breast cancer patients can present with cutaneous manifestations of breast disease at the time of their initial diagnosis; however, cutaneous metastases more often present well after the initial diagnosis and treatment of the breast disease. Prompt recognition of skin metastases by the plastic surgeon, especially during the delayed setting of reconstructive surgery following mastectomy, allows for earlier intervention in treating the systemic spread of the disease. A clinical case of carcinoma erysipeloides presenting in this delayed setting is outlined in the present report, along with a review of the literature.     

睾旁胚胎型横纹肌肉瘤5例报告并文献复习

目的:提高睾旁胚胎型横纹肌肉瘤的诊治水平。方法:回顾性分析5例睾旁胚胎型横纹肌肉瘤患者的临床资料,结合文献复习进行讨论。结果:5例患者中精索胚胎型横纹肌肉瘤2例、附睾胚胎型横纹肌肉瘤2例、鞘膜横纹肌肉瘤1例,临床病理分期Ⅰ期2例,Ⅱ期1例,Ⅳ期2例。5例患者最终均行根治性睾丸切除术及肿块完整切除术。1例Ⅰb期和1例Ⅱ期患者术后采用异环磷酰胺、长春新碱、足叶乙甙、丝裂霉素、顺铂化疗并配合局部放疗,余3例未行进一步治疗。2例Ⅰ期、1例Ⅱ期患者随访28、18、12个月未见复发和转移,1例Ⅳ期患者随访6个月后死于多发转移,1例Ⅳ期随访6个月未见复发和转移,后失访。结论:早期诊断,根治性手术并辅助化疗、放疗是治疗睾旁胚胎型横纹肌肉瘤的有效手段。     

Primary rhabdomyosarcoma of tunica vaginalis misdiagnosing as hydrocele: A case report and literature review

Primary rhabdomyosarcoma of tunica vaginalis is very rare. We report a case of a 15-year-old man presenting as hydrocele. Pre-operatively, no masses were detected by ultrasonography. Hydrocelectomy was performed. At surgery, a 0.8 cm polypoid nodule and diffusely thickened tunica were found. Pathologic examination finally revealed rhabdomyosarcoma. A PET-CT was then performed and indicated scrotal implantation metastasis. The patient underwent radical inguinal orchiectomy and was treated with chemotherapy and radiotherapy after surgery. At 12 months of follow-up, he remained disease-free.     

Metastatic lobular breast cancer presenting with malignant ascites: case report and review of literature

We review the case of an elderly woman with invasive lobular breast cancer presenting as malignant ascites. This unusual presentation is discussed, as well as the options for treatment. Most invasive lobular breast cancers are hormone receptor positive and the roles of hormonal and chemotherapy are reviewed.     

Tuberculous epididymitis： a case report and literature review

Tuberculous epididymitis is a rare urological disease difficult to diagnose. The conventional methods for diagnosis are often time-consuming and invasive. The combined use of scrotal magnetic resonance imaging （MRI） and urinary polymerase chain reaction （PCR）-based assay for mycobacterial DNA （the latter because of its high sensitivity and specificity to demonstrate mycobacterial DNA） is a valuable method for rapid diagnosis of tuberculous epididymitis. We report a 79-year-old man who was admitted with the chief complaints of bilateral scrotal swelling and pain. The combined use of scrotal MRI and urinary PCR allowed prompt diagnosis of tuberculous epididymitis and adequate antituberculous therapy. （Asian J Androl 2005 Sep; 7： 329-332）     

成人睾丸胚胎癌的诊断和治疗(附3例报告并文献复习)

目的 探讨睾丸胚胎癌的临床症状、病理特点及诊疗方法.方法 回顾性分析3例睾丸胚胎癌的临床资料并总结国内外病理文献.3例中Ⅰ期2例、Ⅲ期1例,于根治性睾丸切除术基础上采用腹膜后淋巴结清扫术及化疗等综合治疗.结果 3例病理诊断均为睾丸胚胎癌,1例术后辅助化疗.3例均获随访,随访时间1～3年,1例死于全身广泛转移,其余2例均健康生存.结论 睾丸胚胎癌是一种少见的恶性肿瘤,多数临床症状不明显.诊断主要依靠阴囊理学诊断,B超、CT、血清肿瘤标记物测定等,确诊需要病理学检查,手术切除是其首选的治疗方法.     

假肌源性血管内皮瘤一例分析并文献回顾

目的 探讨假肌源性血管内皮瘤的临床及影像学表现。方法 分析我院一例假肌源性血管内皮瘤的临床表现、实验室检查、影像学及病理学特征,并结合文献进行回顾,总结该病的临床、病理及影像学特征。结果 患者进行实验室及影像学检查后,行右侧髂骨肿物及右臀部皮下肿物切除术,术后恢复良好。结论 假肌源性血管内皮瘤是一种少见的低~中度恶性的血管内皮瘤,影像学上具有软组织肿瘤的特点,熟悉其临床表现、影像学及病理学特征,有助于对该病的诊断及鉴别诊断。     

假肌源性血管内皮瘤一例分析并文献回顾

目的 探讨假肌源性血管内皮瘤的临床及影像学表现。方法 分析我院一例假肌源性血管内皮瘤的临床表现、实验室检查、影像学及病理学特征,并结合文献进行回顾,总结该病的临床、病理及影像学特征。结果 患者进行实验室及影像学检查后,行右侧髂骨肿物及右臀部皮下肿物切除术,术后恢复良好。结论 假肌源性血管内皮瘤是一种少见的低~中度恶性的血管内皮瘤,影像学上具有软组织肿瘤的特点,熟悉其临床表现、影像学及病理学特征,有助于对该病的诊断及鉴别诊断。     

Metastatic malignant melanoma to the foot and ankle: A review of the literature and case report

The lower extremity is a frequent site for malignant melanomas. However, skeletal metastases involving the foot and ankle are a rarity. Nearly all documented cases of secondary pedal bone metastasis have originated from a primary subungual melanoma. The following case study illustrates an unusual skeletal metastasis to the foot and ankle arising from a primary malignant melanoma of the torso.     

非牧区跳跃性布鲁氏菌性脊柱炎1例并文献复习

目的探讨布鲁氏菌性脊柱炎诊治特点,特别是在MRI上的特征,提高对该病的认识。方法回顾性分析本院第一例确诊的布鲁氏菌性脊柱炎并文献复习该病的影像学表现及诊治。结果布鲁氏菌性脊柱炎的影像学表现较为复杂多样、特异性不强,MRI具有重要价值。结论MRI对布鲁氏菌性脊柱炎的诊断和鉴别诊断具有重要价值。     

A case of primary rhabdomyosarcoma of the breast

Primary rhabdomyosarcoma of the breast is a rarely reported in adults, and it occurrence is mostly observed in children. We report a case of primary rhabdomyosarcoma of breast in a 40-year-old lady, who presented in early stage and is in complete remission after one year of treatment.     

Inflammatory pseudotumor of the breast: case report and literature review

Inflammatory pseudotumor (IP) is a benign lesion that can affect any tissue in the body and which may be confused clinically and in imaging for malignancy. Despite the widespread performance of breast biopsy, the finding of inflammatory pseudotumor of the breast is exceedingly rare. Excision of the tumor is the treatment of choice, but there is a relatively high rate of recurrence. The aim of this report is to describe the clinical, imaging, and pathologic features in a case of breast IP, the first reported case in a postpartum woman still nursing her infant.     

Nodular hidradenoma of the breast: A case report with literature review

Nodular hidradenoma or clear cell hidradenoma is a rare skin adenexal tumor which arises from eccrine sweat glands. Skin adenexal tumors situated in the breast parenchyma are still very rare and is one of the differential diagnoses of breast tumors. Failure to identify its morphologic features may lead to a mistaken diagnosis and over treatment. We report a case of breast lump, in a 40-year-old lady, which was diagnosed clinically as a malignant breast lump. Final diagnosis of nodular hidradenoma was made only after excision biopsy as fi ne needle aspiration cytology was inconclusive.     

Case report and literature review: Metastatic lobular carcinoma of the breast an unusual presentation

Introduction

Invasive lobular carcinoma is the second most common type of invasive breast carcinoma (between 5% and 15%). The incidence of invasive lobular carcinoma has been increasing while the incidence of invasive duct carcinoma has not changed in the last two decades. This increase is postulated to be secondary to an increased use of combined replacement hormonal therapy. Patients with invasive lobular carcinoma tend to be slightly older than those with non-lobular invasive carcinoma with a reported mean age of 57 years compared to 64 years. On mammography, architectural distortion is more common and microcalcifications less common with invasive lobular carcinoma than invasive ductal carcinoma. The incidence of extrahepatic gastrointestinal (GI) tract metastases observed in autopsy studies varies in the literature from 6% to 18% with the most commonly affected organ being the stomach, followed by colon and rectum. Gastric lesions seem to be slightly more frequent, compared to colorectal lesions (6–18% compared to 8–12%, respectively).

Presentation of case

We present the case of a 70-year-old woman who was referred to our institution with a concurrent gastric and rectal cancer that on further evaluation was diagnosed as metastatic invasive lobular carcinoma of the breast. She has a stage IV clinical T3N1M1 left breast invasive lobular carcinoma (ER positive at 250, PR negative, HER-2/neu 1+ negative) with biopsy proven metastases to left axillary lymph nodes, gastric mucosa, peritoneum, rectal mass, and bone who presented with a partial large bowel obstruction. She is currently being treated with weekly intravenous paclitaxel, bevacizumab that was added after her third cycle, and she is also receiving monthly zoledronic acid. She is currently undergoing her 12-month of treatment and is tolerating it well.Discussion Breast cancer is the most common site-specific cancer in women and is the leading cause of death from cancer for women aged 20–59 years. It accounts for 26% of all newly diagnosed cancers in females and is responsible for 15% of the cancer-related deaths in women.⁹ Breast cancer is one of the most common malignancies that metastasize to the GI tract, along with melanoma, ovarian and bladder cancer.

Conclusion

We present one of the first reports of metastatic lobular breast cancer presenting as a synchronous rectal and gastric tumors. Metastatic lobular carcinoma of the breast is a rare entity with a wide range of clinical presentations. A high level of suspicion, repetition of endoscopic procedures, and a detailed pathological analysis is necessary for early diagnosis, which might help to avoid surgical treatment due to incorrect diagnosis. Patients with a history of breast cancer who present with new gastrointestinal lesions should have these lesions evaluated for evidence of metastasis through histopathologic evaluation and immunohistochemical analysis. Differentiating between a primary GI lesion and metastatic breast cancer will allow initiation of appropriate treatment and help prevent unnecessary operations.     

儿童颌面部横纹肌肉瘤的MRI表现

［摘要］ 目的 探讨儿童颌面部横纹肌肉瘤的MRI影像学表现及其临床特点。方法 回顾性分析我院10例经手术病理证实的儿童颌面部横纹肌肉瘤的临床特点及其MRI表现,并进行文献回顾。结果 10例儿童颌面部横纹肌肉瘤中,发病于颞部者7例,发病于上颌、下颌及咽旁各1例。肿瘤形态不规则,边界稍欠清,MRI上T1WI呈等或稍低信号,T2WI呈稍高或高信号,DWI弥散受限,增强扫描呈明显不均匀强化。肿瘤呈浸润性生长,4例侵犯腮腺,6例侵犯耳道,3例侵犯咽,5侵犯邻近肌肉,6例骨质破坏,3例推压颈内动脉及颈动脉鞘,2例向上延伸至颅底。结论 儿童颌面部横纹肌肉瘤好发于颞部,受累范围较大,侵犯邻近肌肉并形成骨质破坏。MRI能清晰显示肿物及其边界,周围软组织浸润范围及骨质破坏情况,提供全面的影像诊断信息。     

Aggressive fibromatosis of the breast: a case report and literature review

Aggressive fibromatosis is a rare, locally aggressive disease. It constitutes 0.3% of all solid tumors, but the tumor is rarely seen in the breast, particularly without pectoral muscle and fascial involvement. The etiology is unknown, but an association with Gardner's syndrome has been described. Clinical and imaging findings simulate breast carcinoma. A case in a 53-year-old female patient is reported.     

超声诊断困难的原发性乳腺血管肉瘤：一例报告及文献综述

原发性乳腺血管肉瘤很少见,仅占所有乳腺肿瘤的0.04%。在本文中我们讨论一例首诊时超声漏诊的原发性乳腺血管肉瘤患者。该病例报告将回顾相关文献,主要指出超声在乳腺血管肉瘤诊断中的局限性以及其他影像学方法在乳腺血管肉瘤诊断中的必要性。