Verification of validity of gait analysis systems during treadmill walking and running using human pose tracking algorithm

BackgroundThe human tracking algorithm called OpenPose can detect joint points and measure segment and joint angles. However, the validity of gait analysis using OpenPose has not been examined yet.Research questionWhat is the validity of OpenPose-based gait analysis?MethodsTwenty-four healthy young people participated in this study. The participants were assessed during walking and running. Pelvic segment angles, and hip, knee, and ankle joint angles during treadmill walking and running were measured using VICON. Simultaneously, images were captured using digital cameras from the right and back sides. After processing with OpenPose, the corresponding angles were measured from the estimated joint points. To validate these estimations, linear regression analysis was performed, and intraclass correlation coefficients [ICCs (2, 1)] between the data obtained by OpenPose and VICON were calculated. Furthermore, the agreement between the data obtained by OpenPose and VICON was assessed by Bland–Altman analysis.ResultsFor most ranges of motion (ROM) in the sagittal plane, the hip, knee, and ankle joints had large coefficients of determination, without proportional biases. For most peak angles in the sagittal plane, the knee and ankle joints had large coefficients of determination without proportional biases, although the hip joint had nonsignificant coefficients of determination and proportional biases. In particular, for the hip flexion-extension ROM and peak knee flexion angle during running and the knee ROM during slow walking, the ICCs showed good to excellent agreement. However, for the parameters of the pelvis and hip joint in the frontal plane, there were nonsignificant coefficients of determination and poor ICCs with fixed and proportional biases.SignificanceThe lower limb ROM in the sagittal plane during gait can be measured by the OpenPose-based motion analysis system. The markerless systems have the advantage of being more economical and convenient than conventional methods.     

Three dimensional multi-segmental trunk kinematics and kinetics during gait: Test-retest reliability and minimal detectable change

Background and AimTrunk kinematics and kinetics can contribute to more detailed information on gait impairment, however, data about reliability and measurement error of multi-segment trunk on three-dimensional gait analysis (3DGA) is lacking. The aim of this study is to investigate test-retest reliability and MDC of 3DGA kinematic and kinetic data in a sample of healthy individuals, using a two rigid segment model for the trunk.MethodsA test-retest study with a median interval of 7 days and a sample of 23 healthy individuals was conducted. Anthropometric, time-distance parameters and peak values for lower limb and trunk joint angles/moments were computed. The intraclass correlation coefficient (ICC_3,k), standard error of measurement (SEM), minimal detectable change (MDC) and 95% limits of agreement (LOA) were calculated.ResultsWe found acceptable test-retest reliability for most joint angles and a SEM ≤4°. The ICCs were above 0.7 for joint moments and the SEM and MDC were ≤0.2 Nm/kg and ≤0.6 Nm/kg, respectively. Bland–Altman plots with 95% LOA revealed a good agreement and time-distance parameters were all highly repeatable (majority ICCs > 0.90).ConclusionsThe results of this study suggest varied reliability indices for multi-segment trunk joint angles and moments during gait and an acceptable level of error, particularly for sagittal plane parameters. Some parameters showed wide 95% CIs for ICCs and higher SEM%. However, we believe that this study provides preliminary data regarding reliability indices for multi-segment trunk during gait, which may be valuable for clinical reasoning and decision making when dealing with movement disorders.     

Individuals with knee osteoarthritis present increased gait pattern deviations as measured by a knee-specific gait deviation index

BackgroundA biomechanical analysis can provide valuable information on osteoarthritis (OA) gait, but important multidimensional interactions are often ignored. The Gait Deviation Index (GDI) was designed to address the issue of data complexity in gait analyses by providing a single, encompassing, value for one’s deviation from a normative reference group.Research QuestionThe primary aim of this study was to examine differences in a knee-specific GDI among young adults, and older individuals with and without knee OA. Secondarily, we aimed to examine these differences while controlling for gait speed.MethodSagittal and frontal plane knee joint angles and moments were used in the computation of a GDI among young adults, and older individuals with and without knee OA. The GDI was calculated such that scores ≥100% were considered typical young-healthy gait and a 10% decrease below 100 equated to 1 standard deviation from typical gait. Scores were first examined using a one-way analysis of variance, and examined again after correcting for gait speed.ResultsThe GDI was calculated for three groups: young-healthy adults (n = 52), older individuals without knee OA (n = 56), and individuals with knee OA (n = 191). Those with knee osteoarthritis exhibited a mean GDI of 87.2 (11.1), which was significantly lower than young adults (99.6 (10.6); p < 0.001) and older individuals without knee OA (94.3 (11.0); p < 0.001). Differences in GDI remained consistent after controlling for gait speed. Knee OA gait waveforms displayed significant variability across similar GDIs, specifically in frontal plane patterns.ConclusionThose with knee osteoarthritis exhibited lower (worse) GDIs compared to those without knee osteoarthritis and young, healthy individuals. After correcting for gait speed, these findings did not change. The GDI highlighted the significant variability in gait waveforms within individuals with knee OA, but the clinical utility of the GDI score itself remains limited.     

Trunk flexion during walking in people with knee osteoarthritis

BackgroundOver 50% of the body’s mass is concentrated within the head, arms and trunk. Thus, small deviations in the orientation of the trunk, during normal walking, could influence the position of the centre of mass relative to the lower limb joint centres and impact on lower limb biomechanics. However, there are minimal data available on sagittal kinematics of the trunk in people with knee osteoarthritis (OA) during walking.Research questionDo people with knee OA have altered kinematic patterns of the trunk, pelvis or hip compared with healthy control participants during walking?MethodsStatistical parametric mapping was used to compare sagittal and frontal plane kinematic patterns, during walking, between a healthy group and cohort of people with knee OA.ResultsIndividuals with knee OA walked with a mean increase in trunk flexion of 2.6°. Although this difference was more pronounced during early stance, it was maintained across the whole of stance phase. There were no differences, between the groups, in sagittal plane pelvic or hip kinematics. There were also no differences in trunk, pelvic or hip kinematics in the frontal plane.SignificanceMost previous gait research investigating trunk motion in people with knee OA has focused on the frontal plane. However, our data suggest that an increase in sagittal trunk flexion may be a clinical hallmark of people with this disease. Altered trunk flexion could affect joint moments and muscle patterns and therefore our results motivate further research in this area.     

Validity and reliability of 2-dimensional trunk,hip, and knee frontal plane kinematics during single-leg squat,drop jump,and single-leg hop in females with patellofemoral pain

ObjectivesTo investigate validity and between-session reliability of frontal plane trunk, hip, and knee kinematics during three functional tasks in females with patellofemoral pain (PFP).DesignObservational.SettingResearch Laboratory.Participants20 females with PFP (22.7 ± 3.2 years, 69.9 ± 9.2 kg, 167.7 ± 9.6 cm).Main outcome measuresTrunk, hip, and knee frontal plane peak angles during the single leg squat (SLS), drop vertical jump (DVJ), and single leg hop (SLH) kinematics were evaluated using 2-dimensional (2D) and 3-dimensional (3D) motion capture. Participants returned to the lab one week later and competed a second 2D analysis of the functional tasks. Concurrent validity was assessed by evaluating relationship between 2D and 3D frontal plane kinematics with Pearson correlations. Between-session reliability was assessed by evaluating 2D kinematics with intraclass correlation coefficients by a single assessor.ResultsModerate to strong correlations (r = 0.55–0.76, p < .05) were found for frontal plane hip kinematics during all three tasks and the trunk during the SLH. Frontal plane kinematics demonstrated good to excellent test-retest reliability for each of the three tasks, (ICC _(2,1) = 0.70–0.90).Conclusion2D hip joint angles during the three functional tasks were the only valid frontal plane angles. Trunk, hip, and knee 2D frontal plane kinematics ranged between good-excellent reliability.     

Effects of camera viewing angles on tracking kinematic gait patterns using Azure Kinect,Kinect v2 and Orbbec Astra Pro v2

BackgroundDepth sensors could be a portable, affordable, marker-less alternative to three-dimension motion capture systems for gait analysis, but the effects of camera viewing angles on their joint angle tracking performance have not been fully investigated.Research questionsThis study evaluated the accuracies of three depth sensors [Azure Kinect (AK); Kinect v2 (K2); Orbbec Astra (OA)] for tracking kinematic gait patterns during treadmill walking at five camera viewing angles (0°/22.5°/45°/67.5°/90°).MethodsTen healthy subjects performed fifteen treadmill walking trials (3 speeds × 5 viewing angles) using the three depth sensors to measure joint angles in sagittal hip, frontal hip, sagittal knee, and sagittal ankle. Ten walking steps were recorded and averaged for each walking trial. Range of motion in terms of maximum and minimum joint angles measured by the depth sensors were compared with the Vicon motion capture system as the gold standard. Depth sensors tracking accuracies were compared against the Vicon reference using root-mean-square error (RMSE) on the joint angle time series. Effects of different walking speeds, viewing angles, and depth sensors on the tracking accuracy were observed using three-way repeated-measure analysis of variance (ANOVA).ResultsANOVA results on RMSE showed significant interaction effects between viewing angles and depth sensors for sagittal hip [F(8,72) = 4.404, p = 0.005] and for sagittal knee [F(8,72)=13.211, p < 0.001] joint angles. AK had better tracking performance when subjects walked at non-frontal camera viewing angles (22.5°/45°/67.5°/90°); while K2 performed better at frontal viewing angle (0°). The superior tracking performance of AK compared with K2/OA might be attributed to the improved depth sensor resolution and body tracking algorithm.SignificanceResearchers should be cautious about camera viewing angle when using depth sensors for kinematic gait measurements. Our results demonstrated Azure Kinect had good tracking performance of sagittal hip and sagittal knee joint angles during treadmill walking tests at non-frontal camera viewing angles.     

Lower extremity joint moments throughout gait at two speeds more than 4 years after ACL reconstruction

BackgroundLong-term gait adaptations after anterior cruciate ligament reconstruction (ACLR) have been reported. However, it is still unclear if they persist more than 4 years after surgery and if they are affected by gait speed.Research question: To investigate differences between groups, legs and walking speeds for ankle, knee and hip joint moments in three planes throughout the stance phase of gait.MethodsReconstructed participants (n = 20 males, 32.5 years, 5.5 years post-ACLR) and healthy controls (n = 20 males, 30.6 years) took part in the study. Gait analysis was performed in two different speeds (self-selected and 30% faster). Sagittal, frontal and transverse plane external moments were measured for ankle, knee and hip and compared throughout the stance phase using 95% confidence intervals. Significant differences were established as a consecutive 5% of gait cycle in which 95% confidence interval did not overlap.ResultsThe reconstructed leg did not demonstrate higher joint moments; there were largely no differences while there was lower knee external rotation moment compared to the non-preferred leg of the control group. Higher joint moments were observed during fast speed walking on sagittal plane for knee and hip moments in both groups, and in the frontal and transverse plane for ankle moments.SignificanceGait kinetics appear to be largely normalized at a minimum of 4 years after ACLR. Faster walking speed increase lower extremity joint moments.     

Reliability and criterion validity of two-dimensional movement assessments in those with patellofemoral pain

ObjectivesDetermine criterion validity and intra/inter-rater reliability of 2-dimensional (2D) knee frontal plane projection angle (kFPPA), hip frontal plane projection angle (hFPPA), and dynamic valgus index (DVI) during forward step-downs in those with patellofemoral pain (PFP).DesignCross-sectional.SettingUniversity research laboratory.Participants39 participants with PFP (34.18 ± 7.41years, 170± .1 cm, 81.03 ± 19.36 kg, duration of pain: 68.67 ± 85.08months, anterior knee pain scale: 80.49 ± 7.87, visual analog scale:2.08 ± 2.02)Main outcome measuresAverage 3D hip and knee sagittal, frontal, and transverse joint angles and 2D kFPPA, hFPPA, and DVI at maximum knee flexion were variables of interest. 3D DVI was calculated as the sum of hip and knee frontal and transverse angles. 2D kFPPA, hFPPA, and DVI were calculated by two raters independently on two occasions.ResultsIntra- and inter-rater reliability of all 2D angles were excellent. kFPPA was moderately correlated to 3D knee transverse angles. hFPPA was moderately correlated to 3D hip frontal and transverse angles and largely correlated to 3D DVI. 2D DVI was moderately correlated to hip transverse angles.ConclusionkFPPA, hFPPA, and DVI are reliable. hFPPA may be reflective of 3D hip and knee frontal and transverse motion during forward step-downs in those with PFP.     

Is treadmill walking biomechanically comparable to overground walking? A systematic review

BackgroundThe equivalency of treadmill and overground walking has been investigated in a large number of studies. However, no systematic review has been performed on this topic.Research questionThe aim of this study was to compare the biomechanical, electromyographical and energy consumption outcomes of motorized treadmill and overground walking.MethodsFive databases, ScienceDirect, SpringerLink, Web of Science, PubMed, and Scopus, were searched until January 13, 2021. Studies written in English comparing lower limb biomechanics, electromyography and energy consumption during treadmill and overground walking in healthy young adults (20–40 years) were included.ResultsTwenty-two studies (n = 409 participants) were included and evaluated via the Cochrane Collaboration’s tool. These 22 studies showed that some kinematic (reduced pelvic ROM, maximum hip flexion angle for females, maximum knee flexion angle for males and cautious gait pattern), kinetic (sagittal plane joint moments: dorsiflexor moments, knee extensor moments and hip extensor moments and sagittal plane joint powers at the knee and hip joints, peak backwards, lateral and medial COP velocities and propulsive forces during late stance) and electromyographic (lower limbs muscles activities) outcome measures were significantly different for motorized treadmill and overground walking.SignificanceSpatiotemporal, kinematic, kinetic, electromyographic and energy consumption outcome measures were largely comparable for motorized treadmill and overground walking. However, the differences in kinematic, kinetic and electromyographic parameters should be taken into consideration by clinicians, trainers, and researchers when working on new protocols related to patient rehabilitation, fitness rooms or research as to be as close as possible to the outcome measures of overground walking. The protocol registration number is CRD42021236335 (PROSPERO International Prospective Register of Systematic Reviews).     

Concurrent validity and measurement error of stair climb test in people with pre-radiographic to mild knee osteoarthritis

BackgroundStair climbing is the task first affected in patients with knee osteoarthritis (OA); therefore, the precise measurement of time required to climb stairs is important to identify mobility limitations, particularly in the early phase of knee OA.Research questionThis study aimed to examine the test-retest reliability, measurement error, and concurrent validity of the stopwatch-based stair-climb test (SCT) in adults with pre-radiographic to mild knee OA.MethodsFifty-nine participants (mean age, 59.1 [range, 50–69] years; 72.9% female) with Kellgren and Lawrence grade ≤2 disease underwent an 11-step SCT (11-SCT) in accordance with the Osteoarthritis Research Society International recommended method while wearing pressure sensor-mounted standard shoes that is used as a gold standard procedure. Test-retest reliability, measurement errors, and the concurrent validity of the stopwatch-based 11-SCT were evaluated.ResultsThe test-retest reliability of the stopwatch-based 11-SCT was excellent (intra-class correlation coefficient_1,1 [ICC_1,1], 0.952; 95% confidence interval [CI], 0.560 to 0.985; p < 0.001) and the minimal detectable change₉₅ was 0.102 s. Concurrent validity was excellent (ICC_2,1: 0.957; 95% CI: 0.661 to 0.986; p < 0.001).SignificanceThe stopwatch-based 11-SCT had high test-retest reliability and high concurrent validity, which justify its clinical use for identifying mobility limitations in individuals with pre-radiographic to mild knee OA. A difference of 0.2 s in the stopwatch-based 11-SCT time would be considered a true difference beyond a 95% measurement error.     

Reliability and validity of the Kinect V2 for the assessment of lower extremity rehabilitation exercises

BackgroundBesides its initial use as a video gaming system the Kinect might also be suitable to capture human movements in the clinical context. However, the system’s reliability and validity to capture rehabilitation exercises is unclear.Research questionThe purpose of this study was to evaluate the test-retest reliability of lower extremity kinematics during squat, hip abduction and lunge exercises captured by the Kinect and to evaluate the agreement to a reference 3D camera-based motion system.MethodsTwenty-one healthy individuals performed five repetitions of each lower limb exercise on two different days. Movements were simultaneously assessed by the Kinect and the reference 3D motion system. Joint angles and positions of the lower limb were calculated for sagittal and frontal plane. For the inter-session reliability and the agreement between the two systems standard error of measurement (SEM), bias with limits of agreement (LoA) and Pearson Correlation Coefficient (r) were calculated.ResultsParameters indicated varying reliability for the assessed joint angles and positions and decreasing reliability with increasing task complexity. Across all exercises, measurement deviations were shown especially for small movement amplitudes. Variability was acceptable for joint angles and positions during the squat, partially acceptable during the hip abduction and predominately inacceptable during the lunge. The agreement between systems was characterized by systematic errors. Overestimations by the Kinect were apparent for hip flexion during the squat and hip abduction/adduction during the hip abduction exercise as well as for the knee positions during the lunge. Knee and hip flexion during hip abduction and lunge were underestimated by the Kinect.SignificanceThe Kinect system can reliably assess lower limb joint angles and positions during simple exercises. The validity of the system is however restricted. An application in the field of early orthopedic rehabilitation without further development of post-processing techniques seems so far limited.     

Repeated sprints alter mechanical work done by hip and knee,but not ankle,sagittal moments

ObjectivesTo quantify the changes in work done by lower limb joint moments during maximal speed running following a sports-specific repeated running protocol.DesignObservational with repeated-measures.MethodsRecreational athletes (n = 18 (9 females), aged = 26.2 ± 6.2 years) performed 12 maximal 30-m sprints on a non-motorised treadmill. Three-dimensional kinematics and ground reaction forces were subsequently recorded during a 10-m maximal overground sprint before and immediately after the repeated running protocol, from which we calculated work done by sagittal plane hip, knee, and ankle moments. Relative work (J/kg) was reported as a percentage of positive and negative work done by the sum of joint moments.ResultsFollowing the repeated running protocol, maximal sprint speed decreased by 19% and was accompanied by reductions in total positive (−1.47 J/kg) and negative (−0.92 J/kg) work, in addition to work done by hip (−0.43 to −0.82 J/kg) and knee (−0.28 J/kg) moments during swing. Compared to before the repeated running protocol, less relative work was done by hip (−9%) and knee (−3%) extension moments during swing. Reductions in work done by hip and knee joint moments during swing were significantly correlated with reductions in maximum running speed (r = 0.61−0.89, p < 0.05).ConclusionsA sports-specific repeated running protocol resulted in reductions in mechanical work done by sagittal plane hip and knee joint moments during maximal overground sprinting. Interventions focused on maintaining positive work done by the hip flexors/extensors and negative work done by knee flexors/extensors during the swing phase of running may help prevent reductions in speed following repeated sprinting.     

The influence of body mass index and sex on frontal and sagittal plane knee mechanics during walking in young adults

BackgroundObesity and female sex are independent risk factors for knee osteoarthritis and also influence gait mechanics. However, the interaction between obesity and sex on gait mechanics is unclear, which may have implications for tailored gait modification strategies.Research questionThe purpose of this study was to examine the influence of obesity and sex on sagittal and frontal plane knee mechanics during gait in young adults.MethodsForty-eight individuals with (BMI = 33.03 ± 0.59; sex:50 % female; age:21.9 ± 2.6 years) and 48 without obesity (BMI:21.59 ± 0.25; sex:50 % female; age:22.9 ± 3.57 years) matched on age and sex completed over-ground gait assessments at a self-selected speed. Two (BMI) by two (sex) analysis of variance was used to compare knee biomechanics during the first half of stance in the sagittal (knee flexion moment [KFM] and excursion [KFE]) and frontal plane (first peak knee adduction moment [KAM], knee varus velocity [KVV]).ResultsWe observed a BMI by sex interaction for normalized KFM (P = 0.03). Females had smaller normalized KFM compared to males (P = 0.03), but only in individuals without obesity. Males without obesity had larger normalized KFM compared to males with obesity (P = 0.01), while females did not differ between BMI groups. We observed main effects of sex and BMI group, where females exhibited greater normalized KAM (P < 0.01) and KVV (P < 0.01) compared to males, and individuals with obesity walked with greater KVV compared to those without obesity (P < 0.01). All absolute joint moments were greater in individuals with obesity (all P<0.01) and males had greater absolute KFM compared to females (P < 0.01).SignificanceWe observed sex differences in gait mechanics, however, KFM differences between males and females were only evident in individuals without obesity. Further, females and individuals with obesity had a larger KAM and KVV, which may contribute to larger medial compartment joint loading.     

Side to side kinematic gait differences within patients and spatiotemporal and kinematic gait differences between patients with severe knee osteoarthritis and controls measured with inertial sensors

BackgroundKinematic changes associated with knee osteoarthritis (OA) have been traditionally measured with camera-based gait analysis. Lately, inertial sensors have become popular for gait analysis with the advantage of being less time consuming and not requiring a dedicated laboratory.Research questionDo spatiotemporal and discrete kinematic gait parameters measured with the inertial sensor system RehaGait® differ between the affected and unaffected side in patients with unilateral knee OA and between patients with severe knee OA and asymptomatic control subjects? Do these differences have a similar magnitude as those reported in the literature?MethodsTwenty-two patients with unilateral knee OA scheduled for total knee replacement and 46 age matched control subjects were included in this study. Spatiotemporal parameters and sagittal kinematics at the hip, knee, and ankle joint were measured using the RehaGait® system while walking at a self-selected speed for a distance of 20 m and compared between groups.ResultsPatients with knee OA had slower walking speed, longer stride duration, shorter stride length and lower cadence (P < 0.001). Peak knee flexion during stance and swing was lower in the affected than the unaffected leg (-4.8° and -6.1°; P < 0.01). Peak knee flexion during stance and swing (-5.2° and -8.8°; P < 0.01) and knee range of motion during loading response and swing (-3.6° and -4.4°; P < 0.01) were lower than in the control group.SignificanceThese side to side differences within patients and differences between patients with knee OA and control subjects agree with known gait alterations measured with camera-based systems. The RehaGait® inertial sensor system can detect gait alterations in patients with knee OA and is suitable for gait analysis in a clinical environment.     

Can runners maintain a newly learned gait pattern outside a laboratory environment following gait retraining?

BackgroundPrevious peak tibial shock gait retraining programs, which were usually conducted on a treadmill, were reported to be effective on impact loading reduction in runners. However, whether the trained runners can translate the training effect at different running modes (treadmill/overground), or running slopes (uphill/downhill), remains unknown.Research questionIs the training effect from a treadmill-based gait retraining translatable to unconstrained running conditions, including overground and uphill/downhill running?MethodsThe peak tibial shock was measured during treadmill/overground running, as well as level/uphill/downhill running before and after a course of treadmill-based gait retraining. The 8-session training aimed to soften footfalls using real-time biofeedback of tibial shock data. Repeated measures ANOVA was used to examine the effect of training, running mode, and running slope, on a group level. Reliable change index of each participant was used to assess the individual response to the training protocol used in this study.ResultsEighty percent of the participants were responsive to the gait retraining and managed to reduce their peak tibial shock following training. They managed to translate the training effect to treadmill slope running (Level: p < 0.05, Cohen’s d = 1.65; Uphill: p = 0.001, Cohen’s d = 0.91; Downhill: p < 0.05; Cohen’s d = 1.29) and overground level running (p = 0.014, Cohen’s d = 0.85). However, their peak tibial shock were not reduced during overground slope running (Uphill: p = 0.054; Cohen’s d = 0.62; Downhill p = 0.12; Cohen’s d = 0.48).SignificanceOur findings indicated that a newly learned gait pattern may not fully translate to running outside of the laboratory environment.     

Kinematic changes in patients with severe knee osteoarthritis are a result of reduced walking speed rather than disease severity

BackgroundKinematic changes in patients with knee osteoarthritis (OA) have been extensively studied. Concerns have been raised whether the measured spatiotemporal and kinematic alterations are associated with disease progression or merely a result of reduced walking speed.Research question: The purpose of this study was to investigate the effect of walking speed on kinematic parameters in patients with knee OA using statistical parametric mapping (SPM).MethodsTwenty-three patients with unilateral knee OA scheduled for a total knee replacement and 28 age matched control subjects were included in this study. Spatiotemporal parameters and sagittal plane kinematics were measured in the hip, knee, and ankle using the inertial sensors system RehaGait® while walking at a self-selected normal (patients and controls) and slow walking speed (controls) for a distance of 20 m. Gait parameters were compared between groups for self-selected walking speed and for matched walking speed using SPM with independent sample t tests.ResultsAt self-selected walking speed, patients had significantly lower knee flexion during stance (maximum difference, -6.8°) and during swing (-11.0°), as well as higher ankle dorsiflexion during stance phase (+12.5°) and lower peak hip extension at the end of stance compared to controls (+4.2°). At matched speed, there were no significant differences in joint kinematics between groups.SignificanceDifferences in sagittal plane gait kinematics between patients with knee OA and asymptomatic controls appear to be mainly a result of reduced walking speed. These results emphasize the importance of considering walking speed in research on gait kinematics in patients with knee OA and in clinical trials using gait parameters as outcome measures.     

A kinematic and kinetic comparison of overground and treadmill walking in healthy subjects

INTRODUCTION: Gait evaluation protocols using instrumented treadmills will be increasingly used in the near future. For this reason, it must be shown that using instrumented treadmills will produce measures of the ground reaction force adequate for inverse dynamic analysis, and differences between treadmill and overground gait must be well characterized. METHODS: Overground walking kinetics were estimated with the subjects walking at their self-selected comfortable walking speed. For the treadmill gait trials, the subjects walked on two treadmills, such that heel-strike occurred on the forward treadmill and toe-off occurred on the trailing treadmill. The treadmill was set to the average overground walking speed. Overground and treadmill data were evaluated using Vicon Plug-in Gait. The differences between the maxima and minima of kinematic and kinetic parameters for overground and treadmill gait were evaluated. RESULTS: The kinematics of treadmill and overground gait were very similar. Twelve of 22 kinematic parameter maxima were statistically significantly different (p<0.05), but the magnitude of the difference was generally less than 2 degrees . All GRF maxima were found to be statistically significantly smaller for treadmill versus overground gait (p<0.05) as were 15 of 18 moment, and 3 of 6 power maxima. However, the magnitude of the differences was comparable to the variability in normal gait parameters. The sagittal plane ankle moments were not statistically different for treadmill and overground gait. DISCUSSION: We have shown that treadmill gait is qualitatively and quantitatively similar to overground gait. Differences in kinematic and kinetic parameters can be detected in matched comparisons, particularly in the case of kinetic parameters. However, the magnitudes of these differences are all within the range of repeatability of measured kinematic parameters. Thus, the mechanics of treadmill and overground gait are very similar. CLINICAL SIGNIFICANCE: Having demonstrated the essential equivalence of treadmill and overground gait, it is now possible for clinical movement analysis to take advantage of treadmill-based protocols.     

Measuring gait kinematics in patients with severe hip osteoarthritis using wearable sensors

BackgroundThe popularity of inertial sensors in gait analysis is steadily rising. To date, an application of a wearable inertial sensor system for assessing gait in hip osteoarthritis (OA) has not been reported.Research question: Can the known kinematic differences between patients with hip OA and asymptomatic control subjects be measured using the inertial sensor system RehaGait®?MethodsThe patients group consisted of 22 patients with unilateral hip OA scheduled for total hip replacement. Forty-five age matched healthy control subjects served as control group. All subjects walked for a distance of 20 m at their self-selected speed. Spatiotemporal parameters and sagittal kinematics at the hip, knee, and ankle including range of motion (ROM) were measured using the RehaGait® system.ResultsPatients with hip OA walked at a slower walking speed (−0.18 m/s, P < 0.001) and with shorter stride length (−0.16 m, P < 0.001), smaller hip ROM during stance (−11.6°, P < 0.001) and swing (−11.3°, P < 0.001) and smaller knee ROM during terminal stance and swing (−9.0° and−11.5°, P < 0.001). Patients had a smaller hip ROM during stance and swing and smaller knee ROM during terminal stance and swing in the affected compared to the unaffected side (P < 0.001).SignificanceThe differences in spatiotemporal and kinematic gait parameters between patients with hip OA and age matched control subjects assessed using the inertial sensor system agree with those documented for camera-based systems. Hence, the RehaGait® system can measure gait kinematics characteristic for hip OA, and its use in daily clinical practice is feasible.     

Reliability of principal components and discrete parameters of knee angle and moment gait waveforms in individuals with moderate knee osteoarthritis

Gait measures are used to evaluate change in patients with knee osteoarthritis (OA), but reliability has not been fully established in this population. This study examined test-retest reliability of knee angle and moment gait waveform characteristics captured using discrete parameters and principal component analysis (PCA) in individuals with moderate knee OA. Participants (n = 20) underwent three-dimensional gait analysis on two occasions. Motion and force data were captured using two camera banks, infrared light emitting diodes and force plate during self-selected walking. Knee angle and moment waveforms were calculated and analyzed using discrete parameters and by identifying waveform characteristics using PCA. Intraclass correlation coefficients (ICC_2,k) examined test-retest reliability of discrete parameters and PCA derived scores (PC-scores). ICC_2,k values ranged from 0.57 to 0.93 for discrete parameters, 0.52–0.86 for knee angle PC-scores and 0.30–0.94 for the knee moment PC-scores. However, 10 of 13 discrete parameters, six of nine knee angle PC-scores and seven of nine knee moment PC-scores had ICC_2,k values greater than or equal to 0.70. Discrete parameters and PC-scores from flexion angles and adduction moments had the highest ICC_2,k values while adduction angles, rotation angles, and rotation moments had the lowest. Most knee angle and moment waveform characteristics demonstrated ICC_2,k values that could be interpreted as acceptable. Caution should be used when examining adduction and rotation angle magnitudes and early/mid-stance rotation moment magnitudes due to lower ICC_2,k values.     

Gait adaptations with aging in healthy participants and people with knee-joint osteoarthritis

The relationship between age and gait characteristics in people with and without medial compartment osteoarthritis (OA) remains unclear. We aimed to characterize this relationship and to relate biomechanical and structural parameters in a subset of OA patients. Twenty five participants with diagnosed unilateral medial knee OA and 84 healthy participants, with no known knee pathology were recruited. 3D motion capture was used to analyse sagittal and coronal plane gait parameters while participants walked at a comfortable speed. Participants were categorized according to age (18–30, 31–59 and 60+ years), and those with and without OA were compared between and within age groups. In a subset of OA patients, clinically available Computed Tomography images were used to assess joint structure. Differences in coronal plane kinematics at the hip and knee were noted in participants with OA particularly those who were older compared with our healthy controls, as well as increased knee moments. Knee adduction moment correlated with structural parameters in the subset of OA patients. Increased knee moments and altered kinematics were observed in older participants presenting with OA only, which seem to be related to morphological changes in the joint due to OA, as opposed to being related to the initial cause of medial knee OA.