Nevoid Basal Cell Carcinoma Syndrome and Hairy Skin Patches

We report a case of an increasing number of discrete patches of darkly pigmented terminal hair in a patient with nevoid basal cell carcinoma syndrome. This case adds to a small case series of three patients which have previously reported this observation. We report this case to highlight hairy patches as an important clinical feature associated with nevoid basal cell carcinoma syndrome.     

Localization of Peutz-Jeghers macules to psoriatic plaques

We report a case of the Peutz-Jeghers syndrome in which the characteristic pigmented macules developed within preexisting psoriatic plaques in sites extremely unusual for the syndrome. To our knowledge, ours is the first report of such a case in the English literature.     

Ranitidine‐induced black tongue: A case report

Black tongue is a rare, benign, self‐limiting disorder caused by certain conditions and some medications. We report the first case of a child diagnosed with black tongue associated with ranitidine use. We report our case to emphasize the rare side effect of this frequently used drug. Health care professionals should be aware of the likelihood of ranitidine‐induced black tongue in clinical practice.     

Lupus erythematosus simulating syphilis II

We report on a false reactive 19 S (IgM) FTA-Abs test in a case of lupus erythematosus discoides. We are not aware of any similar case described in the literature so far.     

An unusual case: bilateral symmetrical Bowen's disease

We report on an unusual case of bilateral symmetrical Bowen's disease occurring simultaneously on both legs of a 56-year-old male patient. We are not aware of a similar case reported in the literature so far.     

Diffuse plane normolipemic xanthomatosis associated with Takayasu's disease and hyperhomocysteinemia: a case report

We describe a case of diffuse plane normolipemic xanthomatosis (DPNX) associated with Takayasu's disease and hyperhomocysteinemia. This report of an association of Takayasu's disease with hyperhomocysteinemia and DPNX is the only such report in literature. This report corroborates the study by Marcoval et al on 8 patients in 1988 where they highlighted that in every case of DPNX a possible concomitant condition should be always suspected and found out.     

Cutaneous larva migrans contracted in England: a reminder

We report a case of cutaneous larva migrans contracted in England. This case serves as a reminder that the lack of travel abroad should not preclude the diagnosis. We discuss clinical presentation and management of cutaneous larva migrans.     

A case of symptomatic heterozygous female Fabry's disease without detectable mutation in the alpha-galactosidase gene

We report a case of symptomatic heterozygous female Fabry's disease with low alpha-galactosidase blood activity. We could not find any mutations in the coding regions of either the signal peptide or the enzyme subunit in our case.     

Dermatofibroma in a black tattoo: report of a case

Tattooing has been associated with a variety of complications including inflammatory and granulomatous reactions, transmission of infections, and neoplasms. We report a case of a 24-year-old male who presented with a 2-month history of an erythematous nodule involving a newly made tattoo on the right leg. An excisional biopsy was performed and the histopathological evaluation was consistent with dermatofibroma. Only three cases of dermatofibroma associated with tatooing were reported in litetature. We report an additional case and review the literature regarding cutaneous reactions to tattoos.     

A finding of granuloma faciale associated with basal cell carcinoma

The clinical differential diagnosis of violaceous plaques on the face is broad and includes both neoplasms and inflammatory dermatoses. We report the first case of a basal cell carcinoma (BCC) superficial to an underlying granuloma faciale (GF). This is a single case report with clinicopathological correlation. Histological examination of a skin biopsy from the cheek revealed superficial BCC and GF. This case constitutes the first reported finding of coincident GF and BCC.     

Sweet's syndrome in association with non-Hodgkin's lymphoma

Sweet's syndrome is an acute neutrophilic dermatosis frequently found in association with other conditions, particularly inflammatory and neoplastic disease. We report here a patient who developed the condition 2 years after the diagnosis of non-Hodgkin's lymphoma (NHL), in this case affecting: a tonsil, the thirteenth report of such an association. We discuss the diagnosis, investigation and management of Sweet's syndrome in the context of the current case.     

Speckled compound naevus

We report a case of a localized speckled compound naevus arising within normally pigmented skin. Speckled melanocytic naevi are reviewed and the distinctive features of the case enumerated.     

Cutaneous secondary follicular centre cell lymphoma in association with lymphoedema praecox

Summary We report a patient who developed cutaneous metastases in a lymphoedematous leg, from a follicular centre cell lymphoma. in a setting of lymphoedema praecox and recurrent deep-vein thromboses. To our knowledge, this is the first report of such a case. We discuss the possible causes for this localization.     

Aspiration metastases from basal cell carcinoma: the 92nd known case

Was aspiration a cause of lung metastases from basal cell carcinoma? We compared our case to prior reported cases with metastases to the lung attributable to aspiration and considered a prior experimental model. We are convinced we have another case of aspiration metastases from basal cell carcinoma, and hereby report "the 92nd known case."     

Disseminated cutaneous with nasopharyngeal rhinosporidiosis: Light microscopy changes following dapsone therapy

We report a case of disseminated cutaneous and nasopharyngeal rhinosporidiosis in a 48-year-old man. The patient complained of a 6-month history of six subcutaneous skin-coloured swellings on the body and a 5-year history of a pea-sized swelling on the inner aspect of the left lower eyelid. Histopathological examination from one of these lesions showed multiple globular cysts packed with endospores that were typical of rhinosporidiosis. We report this case because of its rarity and to describe the morphological effects of dapsone in promotion of a host inflammatory response to the organism.     

Elastosis colloidalis conglomerata (adult colloid milium, paracolloid of the skin): a maximal manifestation of actinic elastosis?

We report the case of a 50-year-old woman with multiple soft papules in the perioral region resistant to local corticosteroid and antibiotic therapies. Histology revealed elastosis colloidalis conglomerata. There were no hints for a deposition disease. The patient was treated with local retinoids. We report on the therapeutic outcome.     

Malignant mesothelioma presenting as Sister Joseph's nodule

We report a rare case of malignant peritoneal mesothelioma in which the patient presented with umbilical tumor involvement. This case is also compared with other cases of umbilical neoplasm.     

Anaplastic large cell lymphoma and lepromatous leprosy: a rare coexistence

Lepromatous leprosy (LL) has been reported in the literature with Non Hodgkin Lymphoma and rarely with Hodgkin Lymphoma. However, an extensive search of the literature shows no case report describing anaplastic large cell lymphoma (ALCL) in association with LL. We report a case of a young male with LL who was found to have ALCL. This is an interesting case of coexistence of an endemic infectious disease and a rare lymphoma involving the same lymph node, with a brief review of the literature.     

Solitary nodule of the penis as unique manifestation of Rosai-Dorfman disease

We report the case of a 53-year-old man with a solitary nodule located on the inner surface of the prepuce. The lesion was removed and the final diagnosis was Rosai-Dorfman disease (RDD/sinus histiocytosis with massive lymphadenopathy). This report, being the first case of RDD presenting as a single nodule of the penis, broadens the spectrum of the cutaneous expression of RDD.     

Vulvar epithelioid sarcoma metastatic to the scalp. A case report and review of the literature.

We report a case of vulvar epithelioid sarcoma with metastases to the scalp, an inguinal lymph node, lungs, liver, and kidneys. Epithelioid sarcoma typically involves the extremities of young men and may be confused histologically with various benign and malignant processes. Only five cases of primary vulvar epithelioid sarcoma have been previously reported. The present case represents the first report of cutaneous metastases from this primary site. We also review the literature pertaining to the clinical, pathologic, and immunohistochemical features of this rare tumor.