ESTABLISHMENT AND PERPETUATION OF EDUCATIONAL PROGRAMS IN AGING:

No abstract available for this article.     

AGING AND LEISURE BIBLIOGRAPHY

No abstract available for this article.     

老年男性骨密度的增龄改变与骨代谢有关激素的相关性研究

目的探讨老年男性增龄与骨密度(BMD)及骨代谢有关激素的关系。方法123例老年男性按年龄分成3组,分别测定骨密度及血清甲状旁腺素(PTH)、睾酮(T)、雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)并进行比较。结果老年男性BMD随增龄而减少,在股骨近端和髋关节处更为明显(P<0.05),在腰椎不确定;老年男性T、E2处于低水平,而FSH、LH及PTH随增龄而增高,FSH更为明显(P<0.05)。结论随着增龄,老年男性MBD下降,T、E2水平低下,而FSH、LH和PTH水平增高。提示体内骨代谢有关激素的变化,可能是老年男性骨质疏松症发病的重要机制之一。     

PRIAPISM IN SICKLE CELL ANEMIA IN TOGO: PREVALENCE AND KNOWLEDGE OF THIS COMPLICATION

Prevalence of priapism and knowledge on this disease was assessed by interviewing a group of 114 sickle cell anemia patients, 5 years and older, considered to be genotypically homogenous (Benin or #19 haplotype). Prevalence of priapism in homozygous sickle cell patients was 26.3% (30/114) and that of the control group of subjects with Hb AA was 2% (2/102) (the difference was very significant: p = 5.10–7). Actuarial probability of having priapism by 20 years of age was 69 ± 8.5%. Few homozygous patients without a history of priapism (15.8%) have heard about priapism. This lack of knowledge, added to low accessibility of a health care system, may explain the high rate of impotence (31.6%). The results of this study led us to plan a large program of information about priapism and sickle cell disease in the Togolese population.     

ON HOOKWORM ANEMIA: (APLASTIC ANEMIA IN HOOKWORM DISEASE)

We have discussed three types or stages of blood changes in hookworm disease.Attention is directed to a severe irreversible aplastic anemia which occurs not infrequently in hookworm disease. The pathogenesis is obscure, but we believe thatit is due to bone marrow exhaustion following continuous blood loss in the presenceof various factors, including dietary deficiency.

The symptomatology, hematologic and bone marrow findings are described.

     

重组促红细胞生成素对维持性血透患者左心室结构与功能的影响

目的了解重组人促红细胞生成素(rHuEPO)对维持性血透患者左心室结构及功能的影响.方法34例应用rHuEPO纠正贫血同时控制血压和11例单用降压药的血透患者随访6～9个月.结果维持性血透患者左心室肥厚(LVH)发生率高达80%,左室功能也经常受累,尤以舒张功能为主,并出现早.相关分析提示Hb与左室结构、功能相关,贫血是影响LVH和左室功能的重要因素.应用rHuEPO能纠正肾性贫血,并通过改善心脏高排量、高动力状态使LVH逆转,IVST从治疗前11.9±2.27mm到治疗后10.9±2.30mm,LVPWT从11.2±1.29mm到10.0±1.59mm,LVMI从184.5±50.2g/m2到146.1±40.8g/m2,左室舒张功能改善,E/A从治疗前0.87±0.41到1.04±0.39.同时存在贫血和高血压的患者,仅靠降压药控制血压水平,未纠正贫血,LVH不易逆转,左室功能不易改善.结论长期纠正贫血和控制血压有利于血透患者左室结构及功能异常的好转.