针灸及护理干预治疗女性膀胱过度活动症的临床研究

目的 针灸及护理干预治疗女性膀胱过度活动症疗效观察.方法 选择女性膀胱过度活动症患者60例,随机分为对照组和观察组各30例.对照组采用行为干预护理;观察组在与对照组相同的行为干预护理基础上配合针灸治疗,一个疗程(5周)后观察记录两组患者排尿症状和储尿期的单次尿量及膀胱最大容量及尿动力学结果的评估.结果 观察组治疗后在尿频、尿急、夜尿和尿失禁的发生率均少于对照组;观察组治疗后储尿期的单次尿量及膀胱最大容量的改善高于对照组;观察组治疗后尿动力学结果逼尿肌不稳定型的例数少于对照组,差异均有显著意义(P＜0.05).结论 针灸及护理干预治疗女性膀胱过度活动症,能有效改善临床症状.     

泌尿外科膀胱过度活动症患者的行为干预护理

目的探讨认知及行为干预护理对泌尿外科膀胱过度活动症(OAB)患者的护理效果。方法选择本院泌尿外科进行OAB诊断治疗的患者66例,随机分为观察组和对照组各33例。观察组治疗过程中除药物治疗外,还加入认知及行为干预,而对照组采取常规护理,比较2组临床疗效、排尿频率、尿急间隔频率和排尿量情况。结果观察组护理总有效率高于对照组(P 0. 05),观察组排尿频率和尿急间隔频率低于对照组(P 0. 05),排尿量多于对照组(P 0. 05)。结论认知及行为干预护理方式对于OAB患者,护理效果良好。     

对女性膀胱过度活动症患者实施护理干预的研究

目的探讨护理干预对女性膀胱过度活动症(OAB)患者的影响,提高女性OAB患者的生活质量。方法健康教育、盆底肌训练、膀胱训练等。结果实施前后患者症状评分下降,生活质量提高。结论有效护理干预对促进女性OAB患者的康复有积极的意义。     

护理干预强化行为矫正膀胱过度活动症的应用研究

目的探讨护理干预过程中强化行为疗法对膀胱过度活动症(OAB)有效措施。方法选择OAB患者50例,随机分为对照组和观察组各25例。对照组采用常规用药治疗及护理,观察组在与对照组相同用药治疗及护理的基础上,由专科护士制定训练计划实施行为矫正疗法。干预后第1、2、4周对两组患者观察记录排尿症状和生活质量评分。结果观察组在尿频、尿急、夜尿和尿失禁的发生率均少于对照组(P<0.05);观察组在护理干预后1、2、4周QOL评分显著低于对照组,差异有显著意义。结论护理干预过程中强化行为矫正疗法在OAB患者的康复中能有效改善排尿症状,大大提高了患者的生活质量。     

综合护理干预在女性膀胱过度活动症病人中的应用

[目的]探讨综合护理干预在女性膀胱过度活动症病人治疗过程中的效果。[方法]将80例成年女性膀胱过度活动症病人随机分为对照组和观察组各40例。对照组采用药物治疗及行为疗法,观察组在对照组治疗的基础上加强心理干预、健康教育、强化行为疗法,出院后定期进行系统的电话随访,干预2周、4周、8周后观察记录两组病人排尿症状、排尿间隔时间和储尿期的单次尿量。[结果]干预4周、8周后观察组病人尿频、尿急、夜尿和尿失禁发生率均低于对照组(P<0.05);观察组病人排尿间隔时间和储尿期的单次尿量比对照组延长或增加(P<0.05)。[结论]综合护理干预治疗成年女性膀胱过度活动症能有效改善排尿症状。     

综合护理干预对膀胱过度活动症患者的影响

目的探讨综合护理干预在膀胱过度活动症(OAB)患者治疗过程中的临床效果。方法将收治的OAB患者90例随机分为对照组(45例)和观察组(45例)。对照组采用药物治疗,观察组在对照组治疗的基础上给予心理干预、健康教育、膀胱训练、盆底肌锻炼、生活方式干预及出院指导等综合护理干预,干预第7天、15天、30天观察患者排尿症状、储尿期的单次尿量和膀胱最大容量情况,评价生活质量(QOL)。结果①干预第15天、30天观察组患者尿频、尿急和夜尿发生率均低于对照组。②干预后2组储尿期的单次尿量及膀胱最大容量逐渐升高,观察组高于对照组。③干预第15天、30天观察组的QOL评分低于对照组。结论在药物治疗的基础上实施综合护理干预治疗OAB,较单纯药物治疗更能有效地改善排尿症状,提高患者的生活质量。     

盆底肌电刺激治疗老年女性膀胱过度活动症

膀胱过度活动症(overactive bladder,OAB)是指由于逼尿肌无抑制性收缩引起的尿急、尿频和／或急迫性尿失禁症状。据资料显示：逼尿肌收缩患病率随年龄而升高,女性高于男性,不同年龄组的患病率从3%～43％不等,超过70岁的女性发病率高达50%,是老年女性尿失禁的主要原因之一,治疗较棘手。我院2003年1～12月对37例OAB患者进行盆底电刺激治疗,取得满意效果,现报告如下。     

循证护理对中年女性膀胱过度活动症患者的影响

目的研究循证护理对中年女性膀胱过度活动症(BHD)患者症状改善及护理满意度的影响。方法选取2015年2月至2017年8月该院收治的中年女性BHD患者96例,以随机抽签法均分成研究组与对照组,各48例。对照组实施常规护理,研究组实施循证护理,两组均进行为期1年的干预。比较两组患者在症状改善、护理满意度、干预前后心理状态以及生活质量方面的差异。结果干预后3个月、6个月、12个月研究组患者的症状改善率均明显高于对照组,差异有统计学意义(均P<0.05)。干预后,研究组患者的护理满意度高于对照组,SAS、SDS评分明显低于对照组,各项SF-36评分明显高于对照组,差异均有统计学意义(均P<0.05)。结论循证护理可显著改善中年女性BHD患者的临床症状,提高患者的护理满意度,同时有利于缓解患者的不良心理情绪,提高其生活质量。     

女性膀胱过度活动症之辨证论治

膀胱过度活动症(OAB)是一种以尿急症状为特征的征候群,常伴有尿频和夜尿症状,可伴或不伴有急迫性尿失禁。尿动力学上可表现为逼尿肌过度活动,也可为其他形式的尿道———膀胱功能障碍。〔1〕女性OAB多发生于中年已婚患者,发作突然,周期性发作,不包括由急性尿路感染或其他形式的     

膀胱过度活动症症状评分表评估膀胱过度活动症的临床研究

目的 确定膀胱过度活动症症状评分表(OABSS)在评价膀胱过度活动症(OAB)中的临床应用价值.方法 初发的OAB患者接受抗毒蕈碱药物托特罗定治疗.在基线期及12周治疗后完成3 d排尿日记和OABSS,通过对比分析治疗前后相关指标的变化、变量的一致性和变化的相关性.结果 本次研究包括59例患者,男22例,女37例,年龄(31.1±9.6)岁,OABSS和相应的3 d排尿日记均显示有统计学意义的疗效改善变化.OABSS中尿急评分的效应值最大(2.10),总评分效应值1.55,排尿日记中尿急评分效应值0.92.OABSS中除白天排尿次数外,其余效应值均大于相应排尿日记的效应值,标准反应均数的变化与效应值的变化相同.OABSS中项目评分和相应排尿日记的变量在基线期及12周治疗后有良好的一致性.急迫性尿失禁及夜尿在OABSS和相应排尿日记的变量有高度相关性.结论 OABSS对治疗相关OAB症候群变化有高度敏感性,在日常临床实践中,OABSS借其简易性及可靠性,可成为排尿日记之外的一种可供选择的评估症状和疗效的工具.     

盆底肌训练结合盐酸奥昔布宁在缓解女性膀胱过度活动症中的效果

目的探讨盆底肌训练在缓解女性膀胱过度活动症(OAB)患者症状中的效果。方法选取120例女性OAB患者中配合完成研究者110例,随机分为观察组50例(盆底肌训练加盐酸奥昔布宁治疗)和对照组60例(常规盐酸奥昔布宁治疗),比较2组患者干预前及干预14 d、30 d、90 d、6个月的膀胱过度活动症症状评分(OABSS),比较2组患者干预前及干预14 d、30 d、90 d的盆底肌肌力牛津分级,并比较2组患者干预前及干预90 d、6个月的King生活质量量表评分。结果治疗30 d、90 d后,观察组患者盆底肌力得分分别为(3.23±0.52)、(3.49±0.50)分,高于对照组的(3.03±0.54)、(2.97±0.62)分,差异有统计学意义(P0.05);治疗后6个月随访时,观察组OABSS评分为(1.17±1.87)分,低于对照组的(2.56±2.03)分,差异有统计学意义(P0.05);治疗90 d后,2组King生活质量量表中总体健康感受、行为受限、排尿问题严重性、运动受限、社交受限、症状严重程度得分比较,差异有统计学意义(P0.05)。结论盆底肌训练结合盐酸奥昔布宁治疗能有效缓解女性OAB症状。     

Persistence with antimuscarinic therapy in patients with overactive bladder

Overactive bladder (OAB) is a chronic condition, which impacts patients' health and quality of life. The primary symptoms of OAB are distressing and may interfere with work, psychosocial and sexual functioning. OAB also is associated with increased risk of urinary tract infections, fractures from falls, skin infections and depression. Patient's concerns about the effects of incontinence on lifestyle highlight the need to restore continence. The mainstay of treatment is antimuscarinic drug therapy, which may often produce only modest reductions in OAB symptoms and may be accompanied by bothersome adverse effects, leading to poor adherence to prescribed medications. Successful treatment of OAB depends on persistence with the prescribed medication, and efficacy and tolerability are key influencers of persistence. New antimuscarinic agents are now available for treating OAB that significantly improve symptoms of incontinence, urgency and frequency with few adverse effects. An improved efficacy and tolerability profile should result in greater patient satisfaction and persistence with therapy during long-term therapy.     

盆底肌锻炼联合膀胱训练治疗前列腺癌根治术后尿失禁的疗效观察

目的:探讨盆底肌锻炼联合膀胱训练对前列腺癌根治术后尿失禁的治疗效果。方法:回顾分析我院8例前列腺癌根治术后出现尿失禁的患者采用盆底肌锻炼联合膀胱训练的治疗措施后患者控尿能力改变的情况。结果:治疗后LT、ICI-Q-SF1及1小时尿垫试验显著低于治疗前(P0.05),而PVLP和PMUC显著高于治疗前(P0.05)。8例术后不同程度尿失禁患者,治愈5例(62.5%),有效2例(25.0%),无效1例(12.5%)。术后控尿总有效率为87.5%。结论:盆底肌联合膀胱训练的综合康复锻炼在治疗前列腺癌根治术后尿失禁的控制方面有良好的效果,是一种相对无损伤、简便、安全、有效的治疗方法。     

护理干预在产后早期盆底功能康复中的效果

目的探讨护理干预对盆底功能障碍疾病患者早期盆底功能恢复的效果。方法选取本院80例盆底功能障碍性疾病患者,按照数字表法随机分成对照组与试验组,分别给予常规护理、护理干预措施实施护理,比较2组患者的盆底功能恢复及其他相应指标情况。结果试验组中5级肌力患者(65.00%)与对照组(30.00%)比较显著较高(P0.05);试验组患者护理后的产后压力性尿失禁、粪失禁显著低于对照组,性生活满意程度(90.00%)与对照组(55.00%)比较显著较高(P0.05)。结论盆底功能障碍疾病患者实施护理干预后对其早期盆底功能效果影响显著,可以改善患者盆底肌力,提高满意程度,减少并发症。     

行为疗法治疗女性轻中度压力性尿失禁的疗效观察

[目的]观察行为疗法治疗女性轻、中度压力性尿失禁的效果.[方法]选择31例女性压力性尿失禁病人,进行行为训练,包括盆底肌锻炼、尿急训练、膀胱功能训练、生活方式干预.治疗观察12周,评价其疗效.[结果]轻度组总有效率91.3%,中度组总有效率62.5%.[结论]行为疗法对女性轻、中度压力性尿失禁治疗效果满意.     

Group training for overactive bladder in female patients: a clinical,randomized, non‐blinded study

Bladder training (BT) given individually for overactive bladder symptoms (OAB) is time consuming, and patients tend to need reinforcement. We hypothesized that a specified BT programme for female OAB patients performed as group training would have the same effect as the identical programme used for individual training. A randomized, controlled, non‐blinded trial in six hospital‐situated clinics in Denmark. A total of 91 women were randomized to either individual BT or group BT (three–four patients in each group). In both settings BT was to be performed daily for a 2‐month period supported by a diary and with three training sessions at the hospital coached by a continence nurse. All analyses were performed as intention‐to‐treat. Main outcome measures were urgency episodes, urgency incontinence episodes and scores from a symptom‐specific visual analogue scale (VAS). A total of 38 women with individual BT and 41 with group BT were included in the analyses. No significant differences in urgency episodes, urgency incontinence episodes, voiding frequency between the two settings were observed after treatment. Neither did scores from the VAS scale differ. Median values showed a daily 50% reduction in urgency incontinence episodes. Daily voiding frequency of 8·5–10 was reduced to 7·5 voidings. Women were equally satisfied with the programme in both settings. Compliance in training was equal, and no serious adverse events were reported in either setting. This particular BT programme for female OAB patients showed no difference between group training and individual training with respect to clinical end points, patient satisfaction or compliance.     

Intradetrusor onabotulinumtoxinA for overactive bladder

Introduction: Overactive bladder is a life-compromising disease that affects approximately 11.8% of all men and women, with increasing rates in the elderly. The mainstay of pharmacotherapy for this disease, anticholinergics, has up to a 71% discontinuation rate at 6 months. The emerging data of intradetrusor onabotulinumtoxinA (onabotA) use for treatment of idiopathic overactive bladder is showing to be an efficacious and well-tolerated alternative to the mainstay of therapy.

Areas covered: This study covers the use of onabotA and its use for idiopathic overactive bladder, stemming from its use in neurogenic detrusor overactivity, by evaluating the conclusions of current studies. A literature search and review was carried out for onabotA in treatment of overactive bladder using PubMed.

Expert opinion: Multiple randomized clinical trials have shown that intradetrusor injection with onabotA is effective in treating non-neurogenic bladder with promising efficacy in patients who have failed traditional pharmacotherapy. This treatment may be superior in certain patients due to its higher rate of compliance and higher rates of complete symptom resolution. Long-term studies are needed.