综合性护理干预对妇产科患者术后疼痛情况及满意度的影响

目的:分析并探讨综合性护理干预对妇产科患者术后疼痛情况以及患者满意度的影响,以提高护理质量。方法:选择进行手术治疗的妇产科疾病患者106例,按照随机数表的方法随机将其分为观察组和对照组两组各53例,两组患者在手术后均给予护理干预,其中对照组给予常规护理干预,观察组给予患者综合护理干预,观察并比较两组患者的术后疼痛情况和满意度。结果:对照组患者的疼痛缓解有效率为83.02%,观察组患者的疼痛缓解有效率为96.23%,观察组明显高于对照组,且两组相比差异具有统计学意义(P<0.05);观察组患者的满意度为96.23%,对照组患者的满意度为77.36%,观察组明显高于对照组,且两组相比差异具有统计学意义(P<0.05)。结论:综合性护理干预应用于妇产科患者术后护理中,能够有效提高疼痛护理效果,减少患者的痛苦,患者的满意度也得到了提高,建议在临床上推广应用。     

综合性护理干预在妇产科术后疼痛中的应用效果分析

目的探讨综合性护理干预对妇产科患者术后疼痛的影响效果。方法选取2015年1月-2016年1月本院妇产科收治的手术患者100例作为观察对象,将其随机分为观察组与对照组,每组患者各50例,其中对照组患者给予常规护理措施,观察组患者在常规护理的基础上应用综合性护理措施进行护理,对比分析两组患者的疼痛改善情况以及护理满意度。结果观察组患者疼痛改善有效率为98.0%,对照组患者疼痛改善有效率为76.0%,两组比较差异显著(P0.05),观察组明显优于对照组;观察组患者的护理满意度为96.0%,对照组患者的护理满意度为74.0%,两组比较差异具有统计学意义(P0.05)。结论良好的护理干预措施可以有效提高妇产科术后疼痛患者的疼痛症状,提高患者对护理工作的满意度,值得临床推广应用。     

对136例妇产科手术患者术后腹部切口进行护理干预的影响分析

目的:探讨妇产科手术患者术后腹部切口实施护理干预的效果。方法:选择我院2014年1月至2016年1月我院妇产科行手术的236例患者作为研究对象,将其随机分为护理组(n=136)和对照组(n=100),对照组予以常规护理方法,护理组在对照组基础上予以综合护理干预,比较两组患者的术后伤口愈合率、肛门排气时间、住院时间、不良反应发生率与护理满意度。结果:两组患者术后各项指标比较,护理组伤口愈合率与肛门排气时间、住院时间均优于对照组(P0.05);两组患者不良反应发生率,护理组总发生率为11.03%(15例),对照组总发生率为44.00(44例),护理组发生率明显低于对照组(P0.05);两组患者护理满意度比较,护理组满意率为93.38%(127例)对照组满意率为83.00(83例),护理组满意率明显高于对照组(P0.05)。结论:对妇产科手术患者术后腹部切口进行综合护理干预,不仅能够提高患者的护理效果与护理满意度,更能降低患者的疼痛不适感,值得临床广泛应用。     

护理干预对普外科术后疼痛及护理满意度的影响观察

目的观察护理干预对普外科术后疼痛及护理满意度的影响。方法以我院普外科行手术治疗的120例患者为研究对象,随机将其分为两组,即实验组(n=60)和参照组(n=60),参照组给予常规护理干预措施,实验组给予综合护理干预措施,对比两组患者护理前后疼痛情况,并评估其护理满意度。结果相较于参照组,实验组经综合护理干预后术后VAS评分显著低于对照组,疼痛得以有效改善;参照组护理满意度为85.00%,实验组为98.33%,实验组明显高于参照组,组间对比存在显著差异(P0.05)。结论普外科行手术治疗者采用综合护理干预可显著改善其术后疼痛情况,并有助于促进患者护理满意度的提高,可在临床推广应用。     

不同体位预防妇产科术后深静脉血栓的效果分析

目的:探讨针对性体位干预对妇产科手术后下肢深静脉血栓形成(LEDVT)的预防效果。方法:将406例妇产科手术患者随机分为两组,观察组(n=203)术后均接受针对性体位干预,对照组(n=203)患者仅接受常规治疗及护理,对比两组患者术后下肢肿胀及疼痛、小腿腓肠肌Homans征阳性、LEDVT形成的情况。结果:观察组手术患者无确诊为手术后并发LEDVT者,对照组术后确诊为LEDVT者5例(2.46%),对照组LEDVT发生率显著高于观察组,差异有统计学意义(字2=5.062344,P=0.024451)。结论:针对性体位干预措施能够有效防治妇产科手术后下肢深静脉血栓形成,有利于减少术后并发症并促进恢复。     

舒适护理对妇科患者术后疼痛及满意度影响分析

目的:探讨舒适护理对妇科患者术后疼痛及满意度影响。方法:将我院2015年3月至2016年3月间收治的妇科手术患者70例作为临床观察对象,并分为观察组35例及对照组35例。对照组采取常规护理,观察组给予舒适护理,对比两组患者术后疼痛情况及满意度情况。结果:对照组术后疼痛情况:1级11例(31.43%),2级13例(37.14%),3级11例(31.43%);观察组术后疼痛情况:1级16例(45.71%),2级14例(40.00%),3级5例(14.29%)。观察组术后疼痛情况要优于对照组(P0.05)。观察组满意度为97.14%;对照组满意度为85.71%,观察组满意度要高于对照组(P0.05)。结论:通过舒适护理可有效改善患者疼痛症状,提升其护理满意度。     

整体护理干预对肛瘘患者术后尿潴留发生率及疼痛程度的影响

目的:探究整体护理干预对肛瘘患者术后尿潴留发生率及疼痛程度的影响。方法:选择我院肛瘘手术患者124例,按入院顺序分为对照组(n=62)与观察组(n=62)。对照组予以常规护理,观察组在常规护理基础上予以整体护理干预。比较两组干预后护理满意度,术后12h、1d、2d、3d疼痛评分(VAS)及术后排尿情况。结果:经干预,观察组术后12h、1d、2d、3d的VAS评分较对照组低,术后首次排尿时间较对照组短,且尿潴留、尿路刺激征发生率较对照组低(P<0.05);干预后观察组护理满意度为91.94%,高于对照组的77.42%(P<0.05)。结论:肛瘘手术患者予以整体护理干预可显著降低其术后尿潴留发生率及疼痛程度,改善患者排尿情况及护理满意度。     

个体化疼痛管理在肌筋膜疼痛综合征患者围手术期的应用

目的：探讨个体化疼痛管理在肌筋膜疼痛综合征患者围手术期的应用价值。方法整群选取2014年3月—2015年3月该院收治的94例患肌筋膜疼痛综合征并住院手术治疗患者,随机分为观察组、对照组,每组47例。对照组给予常规护理,观察组在常规护理基础上给予个体化疼痛管理,包括疼痛评估、情绪调节、分散注意力、药物止痛及疼痛教育。比较两组患者术前、术后疼痛视觉模拟评分法(VAS)评分。结果观察组术前1 d、术后1 d疼痛程度均低于对照组,差异具有统计学意义(t=2.21,t=2.69,P﹤0.05)。两组患者出院满意度比较,观察组和对照组满意度分别为97.9%(46/47)和93.6%(44/47),差异具有统计学意义(P﹤0.05)。结论个体化疼痛管理能够有效降低肌筋膜疼痛综合征患者围手术期间术前、术后的疼痛程度,能够提高患者满意度,具有重要临床护理价值。     

探讨急症创伤骨科患者术后疼痛的影响因素及个体化护理效果

目的:研究分析急症创伤骨科患者术后疼痛的影响原因及其对疼痛进行护理所达到的护理效果。方法:选取2012年2月至2015年2月该院收治的急症创伤骨科患者240例,将其分为观察组与对照组各120例,对照组患者给予常规护理,观察组患者实施个性化护理,观察比较两组患者在术后的疼痛程度及其对护理的满意度。结果:术前两组患者的疼痛程度无显著差异(P0.05),但术后观察组患者的疼痛程度显著优于对照组(P0.05)。观察组患者的满意度(98.33%)显著高于对照组(90.00%,P0.05)。结论:临床上应加强对急症创伤骨科患者的术后疼痛进行观察及评估,并针对其进行个性化护理,这一护理模式可有效患者患者术后的疼痛程度并提高护理人员的满意度。     

术后疼痛在妇产科护理中的重要应用

目的：研究术后疼痛在妇产科护理中的应用。方法：选取该院收治的130例妇产科术后疼痛患者随机分为观察组和对照组,对照组患者采用常规护理方式,观察组在常规护理方式的基础上结合术后疼痛护理方式。结果：观察组护理满意度显著高于对照组（P＜0．05）。结论：针对出现术后疼痛的妇产科患者实施全方面的术后疼痛护理,将对患者的生活质量水平提升产生积极的影响,具有一定的临床医学研究价值。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.