| 2007-2009年浙江省余姚市感染性腹泻沙门菌监测结果分析 |
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| 引用本文： | 张怡明,张建群,罗学辉. 2007-2009年浙江省余姚市感染性腹泻沙门菌监测结果分析[J]. 疾病监测, 2010, 25(11): 894-897 |
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| 作者姓名： | 张怡明 张建群 罗学辉 |
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| 作者单位： | 1.余姚市疾病预防控制中心,浙江 余姚 315400 |
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| 摘 要： | 目的了解浙江省余姚市感染性腹泻患者中沙门菌感染情况、血清分型以及各型对抗菌药物的敏感情况,为制定预防措施和临床治疗提供参考依据。方法采集感染性腹泻患者的粪便或肛试标本,依据GB/T 4789.4进行增菌、分离、生化鉴定、血清分型,药敏试验依据WS/T 125-1999测定。结果 719份腹泻患者粪便中检出沙门菌18株,检出率为2.5%。检出率最高的是O4群的鼠伤寒沙门菌,占50.0%;其次是O9群的肠炎沙门菌,占22.22%;阿汞纳、D群、C2群、阿伯丁和鸭沙门菌各1株。18株沙门菌均对头孢西丁、头孢他定、菌必治、氧氟沙星和亚胺培南敏感率为100%;检测发现有7株耐药菌,其中单耐药菌1株,多重耐药菌6株,而鸭沙门菌耐9种抗生素。结论 2007-2009年腹泻患者沙门菌检出率逐年下降,血清分型有其特点。多元耐药以鸭沙门菌明显,头孢类和喹诺酮类抗生菌对治疗沙门菌腹泻患者效果较好。
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| 关 键 词： | 感染性腹泻 沙门菌 监测 耐药性 |
| 收稿时间： | 2010-08-27 |
Surveillance of Salmonella in infectious diarrhea patients in Yuyao city of Zhejiang province ,2007-2009 |
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| ZHANG Yi-ming , ZHANG Jian-qun , LUO Xue-hui. Surveillance of Salmonella in infectious diarrhea patients in Yuyao city of Zhejiang province ,2007-2009[J]. Disease Surveillance, 2010, 25(11): 894-897 |
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| Authors: | ZHANG Yi-ming ZHANG Jian-qun LUO Xue-hui |
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| Affiliation: | 1.Yuyao Municipal Center for Disease Control amd Prevention, Yuyao 315400, Zhejiang, China |
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| Abstract: | Objective To understand the infection status, serotype and drug susceptibility of Salmonella in infectious diarrhea patients in Yuyao and provide evidence for the prevention and clinical treatment. Methods The stool samples and rectal swabs were collected from infectious diarrhea patients to conduct bacteria enrichment, isolation, biochemical identification and serotyping according to GB/T 4789.4. The drug susceptibility test was performed according to WS/T 125 -1999. Results Eighteen strains of Salmonella were detected from 719 stool samples （2. 5% ）. The majority of the strains detected were Salmonella typhimurium 04 （50. 0% ）, followed by Salmonella enteritidis 09 （22. 22% ）. Salmonella agone （ 1 ）, Salmonella serogroup D （ 1 ）. Salmonella serogroup C2 （ 1 ）, Salmonella aberdeen （ 1 ） and Salmonella anatum （1） were detected too. All the strains were sensitive to cefoxitin, ceftazidime, ceftriaxone, ofloxacin and imipenem. Seven drug resistant strains were detected, including 1 single drug resistant strain and 6 multi drug resistant stains. The Salmonella anatum strain was resistant to 9 antibiotics. Conclusion The detection rate of Salmonella in infectious diarrhea patients in Yuyao declined from 2007 to 2009, and the serotypes of detected strains were different. Salmonella anatum was multi drug resistant. Cephalosporins and quinolones were effective in the treatment of Salmonella infection. |
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| Keywords: | infectious diarrhea Salmonella surveillance drug resistance |
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