首页 | 本学科首页   官方微博 | 高级检索  
     


New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis
Authors:M. E. Meek  A. Boobis  I. Cote  V. Dellarco  G. Fotakis  S. Munn  J. Seed  C. Vickers
Affiliation:1. Chemical Risk Assessment, McLaughlin Centre for Population Health Risk Assessment, Ottawa, Ontario, Canada;2. Department of Medicine, Imperial College London, Hammersmith Campus, London, UK;3. National Center for Environmental Assessment, US Environmental Protection Agency, NW, Washington DC, USA;4. Formerly Office of Pesticide Programs, US Environmental Protection Agency, NW, Washington DC, USA;5. European Chemicals Agency, Helsinki, Finland;6. Systems Toxicology Unit, Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Via E. Fermi, 2749, Ispra, VA, Italy;7. Office of Pollution Prevention and Toxics, US Environmental Protection Agency, NW, Washington DC, USA;8. International Programme on Chemical Safety, World Health Organization, Geneva 27, Switzerland
Abstract:
Keywords:key events  mode of action  adverse outcome pathway  human relevance framework  modified Bradford Hill considerations  weight of evidence approach  species concordance analysis  cellular response  tissue response  molecular target
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号