| HPLC法测定胺碘酮在人体血浆中的浓度 |
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| 引用本文： | 周莹, 阮邹荣, 茅涵文. HPLC法测定胺碘酮在人体血浆中的浓度[J]. 中国现代应用药学, 1995, (1): 26-27. |
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| 作者姓名： | 周莹,阮邹荣 茅涵文 |
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| 作者单位： | 浙江医科大学附属二院临床药理研究室(周莹，阮邹荣)，浙江省医学科学院(茅涵文) |
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| 摘 要： | 运用反相HPLC法测定人体血浆中的胺碘酮浓度。用己腈直接沉淀血浆蛋白在HPLC上直接进样,具有操作步骤简便的优点。0.5～10.0ug/ml范围内,日内变异系数4.5～6.1%;日间变异系数5.3～9.6%,最低检测限0.03ug,胺碘酮保留时间6.08min。
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| 关 键 词： | 高效液相色谱法 胺碘酮 人体血浆 浓度 |
HPLC Assay for Amiodarone in Human Plasma |
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| Zhou Ying, Ruan Zourong, Mao Hanwen. HPLC Assay for Amiodarone in Human Plasma[J]. Chinese Journal of Modern Applied Pharmacy, 1995, (1): 26-27. |
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| Authors: | Zhou Ying Ruan Zourong Mao Hanwen |
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| Abstract: | A reversed-phase high performance liquid chromatographic assay is described forthe determination of amiodarone in human plasma. The advantage of the method is its simpleprecipitation of plasm protein with acetonitrile to prepare the samples for HPLC injec |
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| Keywords: | Drug assay Monitoring therapy HPLC Amiod (on page 25) |
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