Circulating immune complexes after splenectomy. |
| |
| Authors: | E A Donadi I F Carvalho R P Falc?o |
| |
| Affiliation: | Department of Clinical Medicine, School of Medicine, Ribeirão Preto, Brazil. |
| |
| Abstract: | Circulating immune complexes were evaluated in 25 patients (age range 10 to 46 years) who had undergone splenectomy for non-malignant conditions by studying a polyethylene glycol insoluble serum fraction. Although the extent of binding to Clq was within normal limits, these patients had increased concentrations of factor B in the immune complex serum fraction. These findings indicate that an unusual type of circulating immune complex may be detected after splenectomy, suggesting a possible role for the spleen in the removal of circulating immune complexes. |
| |
| Keywords: | |
|
|
