| 斑块钙化负荷影响冠状动脉CT血管造影诊断管腔狭窄的准确性 |
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| 引用本文： | 周永, 梁凯轶, 尹小花, 杨兆杰, 赵宾飞. 斑块钙化负荷影响冠状动脉CT血管造影诊断管腔狭窄的准确性[J]. 分子影像学杂志, 2022, 45(6): 871-875. doi: 10.12122/j.issn.1674-4500.2022.06.15 |
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| 作者姓名： | 周永 梁凯轶 尹小花 杨兆杰 赵宾飞 |
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| 作者单位： | 上海市嘉定区中心医院放射科，上海 201800 |
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| 基金项目： | 上海市嘉定区自然科学研究课题JDKW-2020-0022 |
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| 摘 要： | 目的 探究斑块钙化负荷对冠状动脉CT血管造影（CCTA）诊断管腔狭窄准确性的影响。方法 选取上海市嘉定区中心医院放射科于2019年2月~2022年1月收治的100例患者作为研究对象，所有患者均行冠状动脉造影与CCTA检查，钙化容积与钙化积分以血管段为单位进行记录，按照钙化容积与钙化积分不同将患者分为4组，分析各组血管管腔狭窄程度并探究CCTA判断斑块钙化不同容积与积分的管腔狭窄准确性。结果 100例患者中入选的钙化冠状动脉段共396个，按照15段进行计算，以管腔狭窄≥50%为有意义狭窄，得到敏感度、特异性、准确率、阳性预测值与阴性预测值分别为99.03%（204/206）、83.16%（158/ 190）、91.41%（362/396）、86.44%（204/236）、98.75%（158/160）；当钙化容积≤25 mm2、钙化积分≤80分时，敏感度、特异性、准确率、阳性预测值、阴性预测值均为100%；当196 mm2<钙化容积≤1375 mm2时，敏感度、特异性、准确率、阳性预测值、阴性预测值分别为85.71%、36.36%、75.47%、83.72%、40.00%；当钙化积分>200分时，敏感度、特异性、准确率、阳性预测值、阴性预测值分别为92.86%、75.00%、87.50%、89.66%、91.82%；CCTA诊断不同钙化容积管腔狭窄程度与不同钙化积分管腔狭窄程度的敏感度、特异性、准确率、阳性预测值、阴性预测值具有统计学意义（P<0.05），其中诊断0~25 mm2钙化容积管腔狭窄程度与0~80分钙化积分管腔狭窄程度的敏感度、特异性、准确率、阳性预测值、阴性预测值最高。结论 不同斑块钙化负荷对CCTA诊断管腔狭窄程度准确性的影响存在差异，应引起临床重视。
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| 关 键 词： | CT血管造影 冠状动脉造影 钙化负荷 冠状动脉狭窄 准确性 |
| 收稿时间： | 2022-08-12 |
Effect of calcified plaque load on the accuracy of coronary CT angiography in the diagnosis of lumen stenosis |
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| ZHOU Yong, LIANG Kaiyi, YIN Xiaohua, YANG Zhaojie, ZHAO Binfei. Effect of calcified plaque load on the accuracy of coronary CT angiography in the diagnosis of lumen stenosis[J]. Journal of Molecular Imaging, 2022, 45(6): 871-875. doi: 10.12122/j.issn.1674-4500.2022.06.15 |
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| Authors: | ZHOU Yong LIANG Kaiyi YIN Xiaohua YANG Zhaojie ZHAO Binfei |
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| Affiliation: | Department of Radiology, Shanghai Jiading District Central Hospital, Shanghai 201800, China |
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| Abstract: | Objective To investigate the influence of calcified plaque burden on the accuracy of coronary CT angiography (CCTA) in the diagnosis of lumen stenosis. Methods A total of 100 patients who underwent coronary angiography (CAG) and CCTA in the Department of Radiology at Shanghai Jiading District Central Hospital from February 2019 to January 2022 were selected as the research subjects. The calcification volume and calcification score were recorded in vascular segments. The patients were divided into four groups according to the calcification volume and calcification score, and the degree of vascular stenosis in each group was analyzed. The accuracy of CCTA in diagnosing lumen stenoses of different plaque calcification volume and scores was discussed. Results A total of 396 calcified coronary artery segments were selected from the 100 patients. Based on 15 segments, lumen stenosis ≥50% indicated significant stenosis. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 99.03% (204/206), 83.16% (158/190), 91.41% (362/396), 86.44% (204/ 236) and 98.75% (158/160), respectively. Under the condition of calcification volume ≤25 mm2 and calcification score≤80 points, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value all were 100%. Under the condition of 196 mm2 Conclusion Different calcified plaque loads have different influence on the accuracy of CCTA in the diagnosis of lumen stenosis, which deserves attention in clinical practice. |
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| Keywords: | coronary CT angiography coronary angiography calcification load coronary stenosis accuracy |
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