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中国大陆地区克罗恩病临床误诊的汇总分析
引用本文:沈志坤. 中国大陆地区克罗恩病临床误诊的汇总分析[J]. 世界华人消化杂志, 2006, 14(24): 2460-2463
作者姓名:沈志坤
作者单位:湖州师范学院医学院,浙江省,湖州市,313000
摘    要:目的:了解我国大陆地区克罗恩病(Crohn’s disease,CD)的临床特征,尤其是病变部位及其累及情况,以及临床诊断上的误诊情况,为临床医生快速准确地诊断提供重要线索.方法:对我国近50 a来报道的CD文献资料通过计算机CBM与文献追溯检索,对符合文献入选标准的63篇文献有关误诊情况的数据进行摘录、登记、统计分析.结果:计入统计的CD患者共有1644例,误诊为肠梗阻与套叠为19.33%、肠道肿瘤为19.89%、腹部肿块为10.00%、回盲部占位为13.95%、肠结核为14.47%、溃疡性结肠炎为12.25%、慢性肠炎为33.85%、阑尾病变为17.54%.结论:CD的临床表现缺乏特异性,病变侵犯胃肠道任意部位,且常常侵犯多个部位,给临床诊断带来困难,极易导致误诊.

关 键 词:克罗恩病  误诊情况  汇总分析
修稿时间:2006-04-04

A combined analysis of clinical misdiagnosis for Crohns'''' disease in Chinese, mainland
Zhi-Kun Shen. A combined analysis of clinical misdiagnosis for Crohns'''' disease in Chinese, mainland[J]. World Chinese Journal of Digestology, 2006, 14(24): 2460-2463
Authors:Zhi-Kun Shen
Abstract:AIM: To investigate the clinical features of Crohn's disease in China, especially the status, the locations of lesions and its misdiagnosis in clinics. METHODS: The literatures published in the recent 50 years (1950-1959) about CD were colleted from the Chinese database of Biology and Medicine (CBM, 1979-01/2003-12) by computer and tracing back year by year. All the data about the locations of lesions and misdiagnoses, as well as other demography features were recorded, pooled and statistically analyzed. RESULTS: There were 1644 cases of CD patients, of which 19.33% were misdiagnosed as intestinal obstruction and looping, 19.89% as intestinal tumors, 10.00% as abdominal mass, 13.95% as ileocecal space-occupying lesions, 14.47% as intestinal tuberculosis, 12.25% as ul-cerative colitis, 33.85% as chronic enteritis, and 17.54% as appendiceal diseases. CONCLUSION: CD has no specificity on clinical features, can affect any segment (often many segments) of the gastrointestinal tract from the mouth to anus, and induce the diver- sified clinical manifestations and high misdiagnosis.
Keywords:Crohn's disease  Misdiagnosis  Combined analysis
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