Lack of ciprofloxacin ototoxicity after repeated ototopical application. |
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Authors: | J Claes P J Govaerts P H Van de Heyning S Peeters |
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Affiliation: | Department of Otorhinolaryngology, University of Antwerp, Belgium. |
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Abstract: | The possible side effects of ototopically applied ciprofloxacin on inner ear function were investigated. The hearing function of pigmented guinea pigs was evaluated by daily frequency-specific evoked response audiometry after repeated application of the drug to both ears. Ciprofloxacin appeared to have no statistically significant effect on the hearing thresholds of the experimental animals. |
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