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| 结直肠癌与肥胖等多种病因学的关系探讨 | |
| 引用本文： | 姚慧静,袁海鹏. 结直肠癌与肥胖等多种病因学的关系探讨[J]. 中华结直肠疾病电子杂志, 2016, 5(4): 319-322. DOI: 10.3877/cma.j.issn.2095-3224.2016.04.008 |
| 作者姓名： | 姚慧静 袁海鹏 |
| 作者单位： | 1. 271000 山东省泰安市中心医院消化内二科 |
| 摘 要： | 目的肥胖被证实为增加结直肠癌发病风险的重要因素。本研究探讨BMI与结直肠癌发病的关系，为结直肠癌的预防提供参考。 方法选取泰安市中心医院及泰山医学院附属医院202例首次确诊的结直肠癌患者和202名非癌症患者，分析比较两组患者BMI情况。 结果首次确诊的结肠癌患者平均身体质量指数（body mass index，BMI）为25.1±3.5 kg/m2，对照组人群平均BMI为21.2±3.1 kg/m2，结直肠癌患者的BMI明显高于健康对照人群（t=-12.153，P<0.001）。结肠癌患者的BMI与健康对照组比较，在性别（P<0.05）、是否胆囊炎或胆囊切除病史（P<0.05）方面差异均有统计学意义。Logistic回归分析示，BMI值（t=12.171，P<0.001）、有胆囊炎或胆囊切除病史者（t=3.128，P=0.002）及性别（t=3.321，P=0.001）与结直肠癌的发病呈显著正相关关系，和是否糖尿病（t=1.260，P=0.208）及年龄（t=-1.790，P=0.074）与结直肠癌的发病不相关。 结论结直肠癌的发生与BMI情况、是否患有胆囊病者和性别有关。 |
| 关 键 词： | 结直肠肿瘤 肥胖症 身体质量指数 |
| 收稿时间： | 2016-05-19 |
The relationship among colorectal cancer,obesity and other etiologies |
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| Huijing Yao,Haipeng Yuan. The relationship among colorectal cancer,obesity and other etiologies[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2016, 5(4): 319-322. DOI: 10.3877/cma.j.issn.2095-3224.2016.04.008 | |
| Authors: | Huijing Yao Haipeng Yuan |
| Affiliation: | 1. Department of Gastroenterology, Tai′an Central Hospital, Tai′an 271000, China |
| Abstract: | ObjectiveObesity is associated with increased risk of colorectal cancer. This study was aiming to explore the relationship between BMI and colon cancer for prevention and treatment. MethodsClinical data including BMI of 202 colorectal cancer patients and 202 healthy population from Tai′an Central Hospital were analyzed. ResultsThe mean BMI was significantly higher in colorectal cancer patients than in healthy populatioin (25.1±3.5 kg/m2, 21.2±3.1 kg/m2, t=-12.153, P<0.001). When stratified by sex (P<0.05), cholecystopathy (P<0.05), the BMI was always higher in colon cancer patients than in healthy group. Logistic regression analyses showed that BMI (t=12.171, P<0.001), cholecystopathy (t=3.128, P=0.002) and sex (t=3.321, P=0.001) were important risk factors of colon cancer. The diabetes mellitus (t=1.260, P=0.208) and age (t=-1.790, P=0.074) are not associated with colorectal cancer. ConclusionThe occurrence of colorectal cancer is related to BMI, cholecystopathy and sex. |
| Keywords: | Colorectal neoplasms Obesity Body mass index |
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