| 氟对脱矿和再矿化牙釉质表面的影响 |
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| 引用本文： | 吴娜,周学东,郝玉庆. 氟对脱矿和再矿化牙釉质表面的影响[J]. 华西口腔医学杂志, 2012, 30(5): 493-497. DOI: 10.3969/j.issn.1000-1182.2012.05.010 |
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| 作者姓名： | 吴娜 周学东 郝玉庆 |
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| 作者单位： | 1.重庆医科大学附属口腔医院牙体牙髓科； 重庆市口腔疾病与生物医学研究中心， 重庆401147；2.口腔疾病研究国家重点实验室， 四川大学， 成都610041 |
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| 基金项目： | 国家自然科学基金资助项目(0040305401031);重庆市医学重点学科建设经费基金资助项目(2011) |
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| 摘 要： | 目的研究氟对脱矿和再矿化牙釉质表面的影响，探讨氟防龋的作用机理。方法将牛牙釉质标本分为空白对照组（A组）、非氟化组（B组）、低氟化组（C组）和高氟化组（D组）4组，其中低氟化组和高氟化组依次进行氟化实验、脱矿实验和pH循环再矿化实验，非氟化组只进行脱矿实验和pH循环再矿化实验，空白对照组不做处理。在体视显微镜、显微硬度计和扫描电镜下观察各组釉质表面的形态变化，同时测量分析釉质表面显微硬度。结果氟化牙釉质的表面微观形态显著不同，其脱矿损害具有相对完整的表层；氟化组在氟化、脱矿和再矿化后与非氟化组相比，表面显微硬度均有统计学差异（P<0.05）。结论氟化牙釉质可增强牙釉质的抗龋能力和再矿化效能。
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| 关 键 词： | 氟 釉质 脱矿 再矿化 |
| 收稿时间： | 2011-11-15 |
| 修稿时间： | 2012-01-10 |
Effect to demineralization and remineralization of enamel surface by fluorine |
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| Wu Na,Zhou Xuedong,Hao Yuqing. Effect to demineralization and remineralization of enamel surface by fluorine[J]. West China journal of stomatology, 2012, 30(5): 493-497. DOI: 10.3969/j.issn.1000-1182.2012.05.010 |
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| Authors: | Wu Na Zhou Xuedong Hao Yuqing |
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| Affiliation: | 1. Dept. of Conservative Dentistry and Endodontics, The Affiliated Hospital of Stomatology, Chongqing Medical University; Chongqing Research Center for Oral Diseases and Biomedical Science, Chongqing 401147, China; 2. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China |
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| Abstract: | Objective To analyze the mechanism of fluorine by systemic analysis of fluorination-demineralizationremineralization experiments. Methods The enamel specimens were randomly assigned to untreated group（group A）, non-fluoride group（group B）, low-fluoride group（group C） and high-fluoride group（group D）. The in vitro model of fluoride enamel was established in group C and D. Based on that, the establishment of demineralization model and remineralization experiment by pH-cycling in group B, C and D were followed. All enamel specimens were observed by stereomicroscope and scanning electron microscope and compared in surface microhardness value. Results There was distinct difference in micro-morphologic appearance on fluoride enamel surface. Artificial caries of fluoride enamel showed a relatively complete surface, the surface microhardness after demineralization and remineralization in fluoride group was higher than non-fluoride group（P<0.05）. Conclusion The fluorinated enamel can enhance cariostatic potential and remineralization capacity of dental enamel. |
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| Keywords: | fluorine enamel demineralization remineralization |
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