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胃切除术对2型糖尿病患者血糖的影响
引用本文:李曾一,闵锐,李伟,康维明,于健春,李玉秀,王守俊. 胃切除术对2型糖尿病患者血糖的影响[J]. 基础医学与临床, 2012, 32(5): 570-573
作者姓名:李曾一  闵锐  李伟  康维明  于健春  李玉秀  王守俊
作者单位:1. 中国医学科学院北京协和医学院北京协和医院内分泌科卫生部重点实验室,北京100730;郑州大学第一附属医院内分泌科河南省高等院校临床医学重点实验室,河南郑州450000
2. 中国医学科学院北京协和医学院北京协和医院内分泌科卫生部重点实验室,北京,100730
3. 中国医学科学院北京协和医学院北京协和医院基本外科,北京100730;
4. 郑州大学第一附属医院内分泌科河南省高等院校临床医学重点实验室,河南郑州,450000
摘    要:目的探讨影响2型糖尿病胃部切除手术后血糖转归的相关因素,为今后此种治疗方法的患者选择提供参考。方法回顾分析2001年1月-2010年12月在北京协和医院行胃部切除手术的45例2型糖尿病患者的临床资料,以术后血糖或抗糖尿病药物用量降低20%为缓解标准,分为缓解组(29例)和无效组(16例),比较两组年龄、体重指数(BMI)、病程和血糖等因素之间的差异。结果 2型糖尿病缓解组病程为5.5±1.7年,显著短于无效组的10.7±2.3年(P<0.05)。缓解组和无效组的年龄和BMI无显著改变。术前兼有高血压者血压亦无明显变化。结论胃部手术治疗2型糖尿病宜选择病程较短(5年以下)者。本研究结果尚需大样本前瞻性研究进行证实。

关 键 词:胃切除术  2型糖尿病  血糖转归

The influence on glycemia control for type 2 diabetes patients underwent the bariatric surgery passively
LI Zeng-yi , MIN Rui , LI Wei , KANG Wei-ming , YU Jian-chun , LI Yu-xiu , WANG Shou-jun. The influence on glycemia control for type 2 diabetes patients underwent the bariatric surgery passively[J]. Basic Medical Sciences and Clinics, 2012, 32(5): 570-573
Authors:LI Zeng-yi    MIN Rui    LI Wei    KANG Wei-ming    YU Jian-chun    LI Yu-xiu    WANG Shou-jun
Affiliation:1.Key Laboratory of Endocrinology of Ministry of Health,Dept.of Endocrinology;2.Dept.of Basic Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730;3.Dept.of Endocrinology,the First Affiliated Hospital,Zhengzhou 450000,China)
Abstract:Objective To find the contribution of the factors in like gastroctomy glycemia control.Methods The clinical data of 45 patients with T2DM who underwent gastrectomy in Peking Union Medical College Hospital from January 2001 to December 2010 were retrospectively analyzed.The patients were divided into the improved group(29 cases) and the ineffective group(16 cases) with the standard that whether the glucose level or amount of antidiabetic drug reduced for 20% after surgery or not.The data of age,body mass index(BMI),course of T2DM and blood glucose were compared between the improved group and ineffective group.Results There was a significant difference in the course of T2DM between the improved group and ineffective group.Age and BMI had no statistically significant between the improved group and ineffective group impact on type Ⅱ diabetes in addition,the blood pressure didn’t have significant change in patients with both T2DM and hypertension.Conclusions The surgical treatment of T2DM is suitable for patients with shorter courses of T2DM(less than 5 years).The sample size of this study was small,thus prospective studies with large samples are needed to verify this conclusion.
Keywords:gastrectomy  T2DM  glycemia control
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