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炎症在视网膜静脉阻塞性黄斑水肿中的作用
引用本文:栗怡然,朱瑞琳,杨柳. 炎症在视网膜静脉阻塞性黄斑水肿中的作用[J]. 眼科新进展, 2020, 0(1): 090-94. DOI: 10.13389/j.cnki.rao.2020.0023
作者姓名:栗怡然  朱瑞琳  杨柳
作者单位:100034 北京市,北京大学第一医院眼科
基金项目:国家自然科学基金资助(编号:81470650、81670841);北京市自然科学基金资助(编号:7172218)
摘    要:视网膜静脉阻塞性黄斑水肿是造成患者视力下降及致盲的常见原因。研究表明,炎症机制在黄斑水肿的发生过程中发挥了重要作用。视网膜静脉阻塞发生后,局部损伤激活固有免疫活性细胞,合成和释放大量细胞因子,共同参与炎症反应,导致黄斑水肿发生。本文就视网膜静脉阻塞继发黄斑水肿可能的炎症机制作一综述,以期为针对炎症的治疗提供理论依据。

关 键 词:视网膜静脉阻塞  黄斑水肿  炎症

Role of inflammation in macular edema secondary to retinal vein occlusion
LI Yiran,ZHU Ruilin,YANG Liu. Role of inflammation in macular edema secondary to retinal vein occlusion[J]. Recent Advances in Ophthalmology, 2020, 0(1): 090-94. DOI: 10.13389/j.cnki.rao.2020.0023
Authors:LI Yiran  ZHU Ruilin  YANG Liu
Affiliation:Department of Ophthalmology,the Peking University First Hospital,Beijing 100034,ChinaCorresponding author:YANG Liu,E-mail:liu_yang@bjmu.edu.cn
Abstract:Macular edema secondary to retinal vein occlusion is a common reason of visual loss and blindness.Studies have shown that inflammation plays a significant role in the development of macular edema.After the occurrence of retinal vein occlusion,local injury activates resident immune competent cells,promotes synthesis and release of cytokines,and involves in inflammathory response,which contributes to macular edema.The article reviews the mechanism of inflammation in macular edema secondary to retinal vein occlusion,in order to provide the theoretical basis for treatment of inflammation.
Keywords:retinal vein occlusion  macular edema  inflammation
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