A clinico-pathological study of adult histiocytosis X involving the brain. |
| |
| Authors: | K Hasegawa T Mitomi H Kowa T Motoori S Yagisita |
| |
| Affiliation: | Department of Neurology, Kitasato University School of Medicine, Kanagawa, Japan. |
| |
| Abstract: | Adult histiocytosis X involving the CNS caused progressive spastic paraparesis. The diagnosis was made by immunoreactive anti-S100 protein antibody staining and from the presence of Birbeck granules in biopsy specimens of skin lesions. Neuropathological examination showed massive proliferation and infiltration of S-100 containing histiocyte-like cells and reactive astrocytes throughout the CNS. |
| |
| Keywords: | |
|
