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宫颈鳞状细胞癌乳腺转移3例报道并文献复习
引用本文:张 爽1,' target='_blank'>2,张 明2,王跃欣3,康 林4,任聪聪1,' target='_blank'>2,夏冰杰1,' target='_blank'>2,刘士华1,' target='_blank'>2,孟焕平4,赵 静2. 宫颈鳞状细胞癌乳腺转移3例报道并文献复习[J]. 现代肿瘤医学, 2023, 0(2): 305-310. DOI: 10.3969/j.issn.1672-4992.2023.02.020
作者姓名:张 爽1  ' target='_blank'>2  张 明2  王跃欣3  康 林4  任聪聪1  ' target='_blank'>2  夏冰杰1  ' target='_blank'>2  刘士华1  ' target='_blank'>2  孟焕平4  赵 静2
作者单位:1.河北北方学院研究生学院,河北 张家口 075000;2.河北省人民医院肿瘤科;3.腺体外科;4.病理科,河北 石家庄 050051
基金项目:河北省人才工程培养项目(编号:A201903002);河北省卫计委重点科技研究计划(编号:20180013)
摘    要:目的:探讨宫颈鳞状细胞癌乳腺转移的临床病理特征,以期提高对该病的认识。方法:回顾性分析我院3例宫颈鳞状细胞癌乳腺转移患者的临床资料、影像学特征、病理学特征及预后,并复习国内外相关文献。结果:宫颈鳞状细胞癌乳腺转移非常罕见,本文报道3例患者以乳腺肿块就诊,影像学检查无法与原发性乳腺癌相鉴别,通过肿块病理学检查及免疫组化染色确诊为宫颈鳞状细胞癌转移。虽经积极的抗肿瘤综合治疗,但患者生存期仍然极短。结论:乳腺转移性鳞状细胞癌极易误诊为原发性乳腺癌,需结合病史、组织形态学特征及免疫表型等进行诊断和鉴别诊断,避免误诊。宫颈鳞状细胞癌患者一旦出现乳腺转移,生存期短、预后差。

关 键 词:宫颈鳞状细胞癌  宫颈癌乳腺转移  乳腺转移性癌

Breast metastasis of cervical squamous cell carcinoma:Report of 3 cases and literature review
ZHANG Shuang1,' target='_blank'>2,ZHANG Ming2,WANG Yuexin3,KANG Lin4,REN Congcong1,' target='_blank'>2,XIA Bingjie1,' target='_blank'>2,LIU Shihua1,' target='_blank'>2,MENG Huanping4,ZHAO Jing2. Breast metastasis of cervical squamous cell carcinoma:Report of 3 cases and literature review[J]. Journal of Modern Oncology, 2023, 0(2): 305-310. DOI: 10.3969/j.issn.1672-4992.2023.02.020
Authors:ZHANG Shuang1  ' target='_blank'>2  ZHANG Ming2  WANG Yuexin3  KANG Lin4  REN Congcong1  ' target='_blank'>2  XIA Bingjie1  ' target='_blank'>2  LIU Shihua1  ' target='_blank'>2  MENG Huanping4  ZHAO Jing2
Affiliation:1.School of Graduate Studies,Hebei North University,Hebei Zhangjiakou 075000,China;2.Department of Oncology;3.Department of Gland Surgery;4.Department of Pathology,Hebei Provincial People's Hospital,Hebei Shijiazhuang 050051,China.
Abstract:Objective:To discuss the clinicopathological features of breast metastasis of cervical squamous cell carcinoma,so as to guide the clinical diagnosis and treatment of the disease.Methods:The clinical data,imaging features,pathological characteristics and prognosis of three cases patients with breast metastasis of cervical squamous cell carcinoma were retrospectively analyzed and the relevant literatures at home and abroad were reviewed.Results:Breast metastasis of cervical squamous cell carcinoma is very rare.In this paper,we reported three patients with breast masses that could not be distinguished from primary breast cancer on imaging.The diagnosis of metastasis of cervical squamous cell carcinoma was confirmed by pathological biopsy of the lump and immunohistochemical staining.Despite the comprehensive anti-tumor therapy was given to the patient positively,the patient's survival was extremely short.Conclusion:Breast metastatic squamous cell carcinoma is easily misdiagnosed as primary breast cancer.The clinicians need to combine the medical history,histomorphological features and immunophenotype to make the diagnosis and differential diagnosis of the disease,so as to avoide misdiagnosis.Patients with cervical squamous cell carcinoma have a short survival and poor prognosis once they have breast metastasis.
Keywords:cervical squamous cell carcinoma   breast metastases from cervical cancer   metastatic carcinoma of the breast
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