dfrA20, A novel trimethoprim resistance gene from Pasteurella multocida |
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| Authors: | Kehrenberg Corinna Schwarz Stefan |
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| Affiliation: | Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), Neustadt-Mariensee, Germany |
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| Abstract: | A novel trimethoprim resistance gene, designated dfrA20, was detected on the 11-kb plasmid pCCK154 from Pasteurella multocida. The dfrA20 gene codes for a dihydrofolate reductase of 169 amino acids. Sequence comparisons revealed that the DfrA20 protein differed distinctly from all dihydrofolate reductases known so far. |
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