| 多种营养素联合应用对儿童铅中毒影响 |
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| 引用本文： | 宋柏捷, 杨艳晖, 焦广宇. 多种营养素联合应用对儿童铅中毒影响[J]. 中国公共卫生, 2010, 26(10): 1263-1264. DOI: 10.11847/zgggws2010-26-10-23 |
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| 作者姓名： | 宋柏捷 杨艳晖 焦广宇 |
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| 作者单位： | 1.哈尔滨医科大学附属第二医院临床营养教研室, 黑龙江 哈尔滨 150086 |
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| 基金项目： | 黑龙江省卫生厅科研课题 |
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| 摘 要： | 目的 探讨多种营养素联合应用对铅毒性的拮抗作用。方法 采用自身对照及组间对照法,对维生素C、维生素B1及钙、铁、锌、硒6种已知对铅毒性有拮抗作用的营养素进行人体干预研究。结果 试验组血铅平均值由(160.4±29.2)μg/L下降为(125.8±20.1)μg/L;尿铅平均值由(30.4±8.5)μg/L增加为(39.6±11.6)μg/L;与试食前和对照组比较,试食组试食后血铅下降及尿铅排出差异均有统计学意义(P<0.01);试食组相同时间点尿铅排出率高于尿钙、尿锌的排出率(P<0.05),且临床症状有较明显改善(P<0.05)。结论 多种营养素联合应用具有拮抗儿童铅中毒的作用。
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| 关 键 词： | 营养素 铅中毒 拮抗作用 |
| 收稿时间： | 2010-03-21 |
Joint effects of nutrients on lead poisoning in children |
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| SONG Bai-jie, YANG Yan-hui, JIAO Guang-yu. Joint effects of nutrients on lead poisoning in children[J]. Chinese Journal of Public Health, 2010, 26(10): 1263-1264. DOI: 10.11847/zgggws2010-26-10-23 |
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| Authors: | SONG Bai-jie YANG Yan-hui JIAO Guang-yu |
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| Affiliation: | 1.Department of Clinical Nutrition, the Second Affiliated Hospital, Harbin Medical University Harbin 150086, China |
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| Abstract: | Objective To explore the jointe ffects of nutrients against the toxicity of lead.Methods With self-com parison and group-comparison design,six nutrients were tested in a clinical intervention trial.The nutrients were vitam in C, vitam in B1,calcium,iron,zinc,selenium,which have effects of against lead toxicity.Results On the avrage,the nutrients could reduce blood lead from 160.4±29.2 μg/L to 125.8±20.1 μg/L and increase urine lead from 30.4±815 μg/L to 39.6±11.6 μg/L in the experimental group.After the experiment,the experimental group showed significant differences compared with itself and the control group in the descent of blood lead and the elmiination of urine lead(P < 0.01).The elmiination ratio of urine lead was higher than that of urine calcium and urine zinc in the expermiental group on the same tmie point(P < 0.05).The nutrients relieved clinical symptoms of the patients(P < 0.05).Conclusion The joint effects of nutrients against lead poisoning could be achieved by jointadm in istration in children. |
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| Keywords: | nutrient lead poisoning antag on istic action |
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