Affiliation: | 1. Department of Anesthesiology, Centro Hospitalar S?o Jo?o, Oporto, Portugal;2. Department of Health Information and Decision Sciences & Center for Health Technology and Services Research, Faculty of Medicine of the University of Porto, Oporto, Portugal;3. Department of Surgery, Faculty of Medicine of the University of Porto, Oporto, Portugal;4. Department of Experimental Biology, Faculty of Medicine of the University of Porto, Oporto, Portugal |