| Merkel细胞癌合并原位鳞状细胞癌一例并文献复习 |
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| 引用本文： | 朱慧英,张朝霞,周桂芝,王建文,陈声利. Merkel细胞癌合并原位鳞状细胞癌一例并文献复习[J]. 中国麻风皮肤病杂志, 2022, 38(5): 307-309. DOI: 10.12144/zgmfskin202205307 |
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| 作者姓名： | 朱慧英 张朝霞 周桂芝 王建文 陈声利 |
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| 作者单位： | 山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，济南，250022 |
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| 基金项目： | 山东省重点研发计划(重大科技创新工程)项目(编号:2021LCZX07)。 |
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| 摘 要： | Merkel细胞癌是一种罕见的、具有高度侵袭性的皮肤神经内分泌癌，好发于老年人的日光暴露部位，尤其是头颈部(41%～50%),其次是四肢(32%～38%)。Merkel细胞癌可与鳞状细胞癌、鲍温病、基底细胞癌等皮肤肿瘤合并发生。我们报道一例发生在非光暴露部位的Merkel细胞癌合并原位鳞状细胞癌，并对相关文献进行复习。
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| 关 键 词： | Merkel细胞癌 鳞状细胞癌 |
Merkel cell carcinoma combined squamous cell carcinoma in situ: a case report and literature review |
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| ZHU Huiying,ZHANG Zhaoxia,ZHOU Guizhi,WANG Jianwen,CHEN Shengli. Merkel cell carcinoma combined squamous cell carcinoma in situ: a case report and literature review[J]. China Journal of Leprosy and Skin Diseases, 2022, 38(5): 307-309. DOI: 10.12144/zgmfskin202205307 |
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| Authors: | ZHU Huiying ZHANG Zhaoxia ZHOU Guizhi WANG Jianwen CHEN Shengli |
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| Affiliation: | Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China |
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| Abstract: | Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroendocrine carcinoma that primarily arises on skin of head and neck (41%-50%), followed by lower limbs and upper extremities (32%-38%). MCC is susceptible in elderly persons. MCC may occur concurrently with squamous cell carcinoma, Bowen disease, basal cell carcinoma, and (or) other cutaneous malignancies. We report a case of Merkel cell carcinoma with squamous cell carcinoma in situ in a non-photoexposed site and review the related literature. |
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| Keywords: | merkel cell carcinoma squamous cell carcinoma |
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