| VI-RADS联合IVIM序列在膀胱癌肌层侵犯评估中的价值 |
| |
| 引用本文： | 孟庆涛,李军,蒋会东,王雪强,相丽. VI-RADS联合IVIM序列在膀胱癌肌层侵犯评估中的价值[J]. 中华全科医学, 2022, 20(12): 2096-2100. DOI: 10.16766/j.cnki.issn.1674-4152.002778 |
| |
| 作者姓名： | 孟庆涛 李军 蒋会东 王雪强 相丽 |
| |
| 作者单位： | 1.安徽医科大学附属滁州医院 滁州市第一人民医院影像科，安徽 滁州 239001 |
| |
| 基金项目： | 安徽省教育厅高校自然科学研究项目KJ2021A 0312安徽省滁州市科技计划项目(重点研发专项)项目2020ZN008 |
| |
| 摘 要： | 目的 探讨膀胱影像报告和数据系统(VI-RADS)及体素内不相干运动(IVIM)在评估膀胱癌肌层浸润中的价值。 方法 回顾性分析2018年6月—2022年2月在滁州市第一人民医院手术及病理检查证实的膀胱癌患者共50例(52处病灶)，均在本院行膀胱磁共振常规多参数(包括T2WI、DWI、DCE序列)及IVIM序列扫描，其中，非肌层浸润性膀胱癌(NMIBC)30处病灶，肌层浸润性膀胱癌(MIBC)22处病灶。依据VI-RADS对MR各序列图像进行评分，计算不同截断值诊断MIBC的敏感度、特异度、阳性预测值、阴性预测值及准确率；测量病灶IVIM各参数值(ADCst、D、D*及f值)；分别绘制ROC曲线评价VI-RADS、IVIM参数及其联合对肌层浸润的诊断效能。 结果 IVIM序列内ADCst、D及f值在NMIBC组均高于MIBC组，差异有统计学意义(均P＜0.01)，其AUC分别为0.904、0.889和0.780(均P＜0.01)。以VI-RADS≥4分作为截断值预测肌层浸润性膀胱癌，约登指数最大，为0.603，AUC为0.871；其联合ADCst及D值时，约登指数提升为0.636，AUC为0.916。 结论 VI-RADS≥4分及ADCst、D和f值减低均提示膀胱癌侵犯肌层可能性较大，而VI-RADS联合ADCst及D值组合可明显提高诊断效能。
|
| 关 键 词： | 膀胱影像报告和数据系统 体素内不相干运动 扩散加权成像 膀胱癌 肌层侵犯 |
| 收稿时间： | 2022-06-14 |
Value of vesical imaging reporting and data system combined with intravoxel incoherent motion sequences in the evaluation of muscle invasion in bladder cancer |
| |
| Affiliation: | Department of Imaging Diagnosis, Chuzhou Hospital Affiliated to Anhui Medical University, the First People' s Hospital of Chuzhou, Chuzhou, Anhui 239001, China |
| |
| Abstract: | Objective To investigate the value of vesical imaging reporting and data system (VI-RADS) and intravoxel incoherent motion (IVIM) in the diagnosis of muscle invasive bladder cancer (MIBC). Methods A total of 50 cases (52 tumours) with surgery and pathologically confirmed bladder cancer at the First People' s Hospital of Chuzhou from June 2018 to February 2022 were analysed retrospectively. All patients underwent routine multiparameter MRI scan (including T2WI, DWI and DCE sequence) and IVIM sequence before surgery. Among the cases, 30 lesions were non-MIBC (NMIBC), and 22 were MIBC. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of different cut-off values in diagnosing MIBC were calculated by scoring MR images according to VI-RADS. IVIM parameters (ADCst, D, D* and f values) were measured. The diagnostic efficacy of VI-RADS, IVIM parameters and their combinations in muscle invasion was evaluated by receiver operating characteristic (ROC) curve. Results The ADCst, D and f values of the NMIBC group were significantly higher than those of the MIBC group (all P < 0.01), and the areas under curve (AUC) were 0.904, 0.889 and 0.780, respectively (all P < 0.01). Using VI-RADS score ≥ 4 as the cut-off, muscle invasion was predicted with the highest Youden index of 0.603 and AUC of 0.871. When the VI-RADS combined with ADCst and D values, the Yoden index rose to 0.636, and the AUC was 0.916. Conclusion The VI-RADS ≥ 4 and ADCst, D and f values decline, which indicate the greater possibility of muscle invasion of bladder cancer, and the combination of VI-RADS and ADCst and D values can significantly improve the diagnostic efficacy. |
| |
| Keywords: | |
|
| 点击此处可从《中华全科医学》浏览原始摘要信息 |
|
点击此处可从《中华全科医学》下载免费的PDF全文 |
|
