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| 郑州地区食管癌患者术后3个月症状群研究 | |
| 引用本文： | 孙晓丽,秦颖杰,冯光强. 郑州地区食管癌患者术后3个月症状群研究[J]. 华南预防医学, 2022, 48(6): 679-683. DOI: 10.12183/j.scjpm.2022.0679 |
| 作者姓名： | 孙晓丽 秦颖杰 冯光强 |
| 作者单位： | 郑州大学第五附属医院,河南 郑州 450052 |
| 摘 要： | 目的 调查郑州地区食管癌患者术后3个月症状并探讨症状群种类，分析术后症状群影响因素，指导制定症状管理及干预对策。方法 对2018年1月1日至2020年12月31日在郑州大学第五附属医院进行手术治疗的食管癌患者为研究对象纳入研究，在中文版安德森症状评估量表（MDASI-C）基础上自制调查问卷，在术后3个月时对按要求完成术后复诊的患者术后症状发生情况及严重程度进行评估，采用探索性因子分析方法探讨症状群类型及构成，单因素及多重线性回归分析郑州地区食管癌患者术后3个月症状群的影响因素。结果 研究收集到293例食管癌患者的完整资料，症状发生率居于前位的是食欲不振（95.90%）、疲乏（89.42%）、反流（79.86%）、进食困难（78.16%），症状严重程度居于前位的是疲乏（6.05±1.49）分、反流（5.92±1.62）分、食欲不振（5.87±1.53）分、睡眠不安（5.56±1.38）分。通过探索性因子分析得到3种症状群，分别为胃肠道相关症状群、疲乏相关症状群、进食困难-疼痛症状群，症状评分分别为（20.19±3.56）、（18.24±3.10）、（23.92±4.07）分。多重线性回归... |
| 关 键 词： | 食管癌 手术后 症状群 影响因素 |
| 收稿时间： | 2022-01-24 |
Study on symptom groups of patients with esophageal cancer 3 months after operation in Zhengzhou |
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| SUN Xiao-li,QIN Ying-jie,FENG Guang-qiang. Study on symptom groups of patients with esophageal cancer 3 months after operation in Zhengzhou[J]. South China JOurnal of Preventive Medicine, 2022, 48(6): 679-683. DOI: 10.12183/j.scjpm.2022.0679 | |
| Authors: | SUN Xiao-li QIN Ying-jie FENG Guang-qiang |
| Affiliation: | The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China |
| Abstract: | Objective To investigate the symptoms of patients with esophageal cancer 3 months after operation in Zhengzhou and explore the types of symptoms, analyze the influencing factors of postoperative symptoms, and guide the formulation of symptom management and intervention measures. Methods Patients with esophageal cancer who underwent surgery in the Fifth Affiliated Hospital of Zhengzhou University from January 1, 2018, to December 31, 2020, were included in the study. Based on the Chinese Version of the M.D. Anderson Symptom Inventory （MDASI-C）, a self-made questionnaire was used to evaluate the severity of postoperative symptoms of patients who completed the follow-up visit as required 3 months after the operation. Exploratory factor analysis method was used to explore the type and composition of symptom groups. Univariate and multivariate linear regression analysis methods were used to analyze the influencing factors of symptom groups of patients with esophageal cancer 3 months after operation in Zhengzhou. Results The complete data of 293 patients with esophageal cancer were collected in the study. The highest incidence of symptoms was anorexia （95.90%）, fatigue （89.42%）, reflux （79.86%）, and eating difficulty （78.16%）. The most severe symptoms was fatigue （6.05±1.49）, reflux （5.92±1.62）, anorexia （5.87±1.53）, and disturbed sleep （5.56±1.38）. Three symptom groups were obtained by exploratory factor analysis, which were gastrointestinal related symptom group, fatigue-related symptom group, and eating difficulty-pain symptom group, the symptom scores were （20.19±3.56）, （18.24±3.10）, and （23.92±4.07） points, respectively. Univariate and multivariate linear regression analysis showed that age （β’=0.361）, esophageal cancer staging （β’=0.152）, therapeutic modalities （β’=0.378）, and anastomotic site （β’=-0.089） were the influencing factors of gastrointestinal related symptoms; gender （ β’=0.086 ）, age （ β’=2.011 ）, esophageal cancer staging （ β’=1.562 ）, and therapeutic modalities （ β’=0.104 ） were the influencing factors of fatigue-related symptoms; gender （ β’=1.127 ）, esophageal cancer staging （ β’=0.413 ）, therapeutic modalities （ β’=0.459 ）, and anastomotic site （β’=0.518 ） were the influencing factors of eating difficulty-pain symptoms. Conclusion Three months after surgery, patients with esophageal cancer in Zhengzhou have gastrointestinal-related symptoms, fatigue-related symptoms, and eating difficulty-pain symptoms. The occurrence of symptoms is affected by gender, age, esophageal cancer staging, therapeutic modalities, and anastomotic site. It is necessary to establish efficient and individualized management and intervention strategies according to symptoms and their influencing factors. |
| Keywords: | Esophageal cancer Postoperative Symptom group Influencing factor |
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