| 接骨丹胶囊的抗炎镇痛作用 |
| |
| 引用本文： | 林昱,李新田,邱财荣,杨喜民,史锋庆,吴玫. 接骨丹胶囊的抗炎镇痛作用[J]. 中国药师, 2010, 13(4): 543-545 |
| |
| 作者姓名： | 林昱 李新田 邱财荣 杨喜民 史锋庆 吴玫 |
| |
| 作者单位： | 解放军第三医院,陕西宝鸡,721004 |
| |
| 摘 要： | 目的：评价接骨丹胶囊的抗炎镇痛作用。方法：用二甲苯致小鼠耳肿胀、鸡蛋清致大鼠足爪肿胀及大鼠肉芽肿炎症模型，考察接骨丹胶囊的抗炎作用；用小鼠醋酸扭体法和热板法，观察接骨丹胶囊的镇痛作用。结果：接骨丹胶囊灌胃给药。可明显减轻小鼠耳肿胀度，降低鸡蛋清致大鼠足爪肿胀，抑制大鼠肉芽肿；对小鼠醋酸扭体和热板反应均呈剂量相关性镇痛作用。结论：接骨丹胶囊对急慢性炎症反应均有明显的抑制作用，对热和化学刺激引起的疼痛反应有明显的镇痛作用。
|
| 关 键 词： | 接骨丹胶囊 抗炎作用 镇痛作用 |
Anti-inflammatory and Analgesic Effects of Jiegudan Capsules |
| |
| Lin Yu,Li Xintian,Qiu Cairong,Yang Ximin,Shi Fengqing,Wu Mei. Anti-inflammatory and Analgesic Effects of Jiegudan Capsules[J]. China Pharmacist, 2010, 13(4): 543-545 |
| |
| Authors: | Lin Yu Li Xintian Qiu Cairong Yang Ximin Shi Fengqing Wu Mei |
| |
| Affiliation: | ( No. 3 Hospital of PLA, Shanxi Baoji 721004, China) |
| |
| Abstract: | Objective： To study the anti-inflammatory and analgesicts effects of jiegudan capsules. Method： Models of acute in- flammatory reactions of xylene-induced mouse ear edema, aldumin-induced rats paw edema and the chronic inflammatory reaction of pa- per-induced rats granuloma were performed to study the anti-inflammatory effects. Methods of acetic acid-inducod writhing and hot-plate test in mice were used to study the analgeic effect. Result： The xylene-induced mouse ear edema and albumin-induced rat paw edema were significantly suppressed. Paper-induced rat gran~oma was also markedly reduced. The wrihing times of mice induced by acid were decreased and pain threshold was remarkably improved in dose-dependent manner. Conclusion： Jiegudan capsules manifest obvious an- ti-inflammatory effects on acute and chronic inflammatory reactions. The pain reactions induced by heat and chemical stimulus is signifi- candy relieved. |
| |
| Keywords: | Jiegudan capsules Anti-inflammatory effect Analgesic effects |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
