| 孤独症谱系障碍儿童听觉特征分析 |
| |
| 引用本文： | 庞秀明,王晓敏,陈琪,刘晓翠,孙彩虹,王佳. 孤独症谱系障碍儿童听觉特征分析[J]. 中国学校卫生, 2019, 40(4): 496-498,502. DOI: 10.16835/j.cnki.1000-9817.2019.04.006 |
| |
| 作者姓名： | 庞秀明 王晓敏 陈琪 刘晓翠 孙彩虹 王佳 |
| |
| 作者单位： | 黑龙江中医药大学附属第二医院康复中心,哈尔滨,150001 |
| |
| 基金项目： | 黑龙江省自然科学基金项目(QC2018106) |
| |
| 摘 要： | 目的探讨孤独症谱系障碍(autism spectrum disorder, ASD)儿童听觉脑干反应(auditory brainstem response, ABR)各波潜伏期和峰间期的特征及与ASD行为表型间的关联。方法收集哈尔滨市明确诊断的2～6岁ASD儿童90例,应用脑干电位诱发反应仪采集ABR数据,分析ASD儿童左右耳各波潜伏期、峰间期特征及与临床表型的关联。结果ASD儿童左、右耳Ⅰ,Ⅲ,Ⅴ波潜伏期分别为(1.51±0.20)(3.83±0.34)(5.63±0.23)ms;(1.54±0.16)(3.78±0.23)(5.63±0.22)ms,均超过正常均值(P值均<0.05);ASD儿童Ⅰ-Ⅲ(6.6%),Ⅲ-Ⅴ(1.1%),Ⅰ-Ⅴ(3.3%)峰间期较正常儿童延长;<3岁组与3～7岁组ASD儿童相比,左右耳Ⅰ-Ⅲ,Ⅰ-Ⅴ峰间期均明显延长(P值均<0.05)。关联性分析发现,ASD儿童左耳Ⅰ波潜伏期与孤独症诊断访谈量表修订版(ADI-R)社交功能缺陷存在正相关(r=0.45,P<0.05);左耳Ⅰ波潜伏期、Ⅲ-Ⅴ峰间期和右耳Ⅴ波潜伏期与非言语性沟通能力障碍呈正相关(r值分别为0.35,0.39,0.34,P值均<0.05);左、右耳Ⅰ-Ⅲ峰间期与重复刻板行为呈正相关(r值分别为0.39,0.35,P值均<0.05)。结论 ASD儿童存在异常的听觉行为特征,且异常程度与ASD儿童社会交往、沟通及重复刻板行为的严重程度存在明显关联。
|
| 关 键 词： | 孤独性障碍 听觉 儿童 精神卫生 |
Study on the characteristics of auditory in children with autism spectrum disorders |
| |
| PANG Xiuming,WANG Xiaomin,CHEN Qi,LIU Xiaocui,SUN Caihong,WANG Jia. Study on the characteristics of auditory in children with autism spectrum disorders[J]. Chinese Journal of School Health, 2019, 40(4): 496-498,502. DOI: 10.16835/j.cnki.1000-9817.2019.04.006 |
| |
| Authors: | PANG Xiuming WANG Xiaomin CHEN Qi LIU Xiaocui SUN Caihong WANG Jia |
| |
| Affiliation: | (The 2nd Affiliated Hospital of Heilongjiang University Of Chinese Medicine,Harbin(150001), China) |
| |
| Abstract: | Objective To explore the characteristics of Auditory Brainstem Response (ABR) in children with ASD, and analyze their relation with the core symptoms of ASD. Methods Ninty children aged 2-6 with ASD were recruited from Harbin in this study. The data of ABR was collected by using BAEP, and the association among children's absolute latency and interpeak latency of ABR, core symptoms of ASD children's behavior and clinical manifestation was analyzed. Results Compared with the normal average value, children with ASD had longer the absolute latency of wave Ⅰ, Ⅲ, Ⅴ in bilateral ears, which were (1.51±0.20) (3.83±0.34) (5.63±0.23) ms, (1.54±0.16) (3.78±0.23) (5.63±0.22) ms, respectively (P<0.05). Some children's interpeak latency of Ⅰ-Ⅲ, Ⅲ-Ⅴ, Ⅰ-Ⅴ were longer than normal values. Children younger than 3 years old showed prolonged peak intervals of Ⅰ-Ⅲ and Ⅰ-Ⅴ than children in 3-7 years old. The study has also showed that there was positive correlation between the absolute latency of waveⅠin left ear and the social function defect (r=0.45, P<0.05); there was positive correlation between the latency of wave Ⅴin right ear or the latency of waveⅠin left ear or the Ⅰ-Ⅲ peakinterval and non-verbal communication ability dysfunction (r=0.35, 0.39, 0.34, P<0.05); there was positive correlation between the Ⅰ-Ⅲ peak interval and the repeated stereotyped symptoms (r=0.39, 0.35, P<0.05). Conclusion Children with ASD have abnormal auditory behavior. The absolute latency and interpeak latency of ABR is correlated to some parts of core symptoms of ASD. |
| |
| Keywords: | Autistic disorder Auditory perception Child Mental health |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中国学校卫生》浏览原始摘要信息 |
|
点击此处可从《中国学校卫生》下载全文 |
|
