Human papillomavirus‐related basaloid squamous cell carcinoma of the bladder associated with genital tract human papillomavirus infection |
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| Authors: | Alessandro Ginori Aurora Barone Rosa Santopietro Gabriele Barbanti Filippo Cecconi Sergio Antonio Tripodi |
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| Affiliation: | 1. Department of Medical Biotechnologies, Pathology Unit, University of Siena, Siena, Italy;2. Department of Urology, University Hospital of Siena, Siena, Italy |
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| Abstract: | Basaloid squamous cell carcinoma is a biologically aggressive neoplasm mainly found in the head and neck region. Recently, four cases of basaloid squamous cell carcinoma of the bladder have been reported, and three of them occurred in patients with neurogenic bladder, repeated catheterizations and human papillomavirus infection of the urinary tract. To the best of our knowledge, none of the patients affected by basaloid squamous cell carcinoma of the bladder described in the literature had documented genital involvement by human papillomavirus. Herein, we describe the case of a woman with neurogenic bladder affected by basaloid squamous cell carcinoma of the bladder and by a concomitant genital tract human papillomavirus infection. |
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| Keywords: | basaloid squamous cell carcinoma bladder epithelial– mesenchymal transition human papillomavirus p16 |
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