| 肾移植术后感染巨细胞病毒性肺炎的多因素分析 |
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| 引用本文： | 魏强,于立新,邓文锋,叶俊生. 肾移植术后感染巨细胞病毒性肺炎的多因素分析[J]. 南方医科大学学报, 2009, 29(6): 1182 |
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| 作者姓名： | 魏强 于立新 邓文锋 叶俊生 |
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| 作者单位： | 南方医科大学南方医院器官移植科,广东,广州,50515 |
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| 摘 要： | 目的 探讨肾移植术后感染巨细胞病毒性(CMV)肺炎的多种高危因素,提出早期预防措施.方法 回顾2005年1月～2007年12月间曾在我院接受同种异体肾脏移植术并因发生CMV肺炎而再次入院患者28例,采用卡方检验及多元logistie回归分析方法分别对影响CMV肺炎的一些凶素进行逐步分析.结果 与CMV肺炎感染密切相关的独立因素包括:受者年龄、急性排斥反应、术前透析时间、移植肾功能延迟恢复、受者PRA水平、供体CMV血清学、麦考酚酸酯的应用;logistic回归分析认为供体CMV血清学IgG(+)、术后急性排斥反应及术前长期血透时间为高危因素.结论 肾移植术后为减少巨细胞病毒性肺炎的发生发展,抑制早期急性排斥反应非常重要,同时尽量选择血清学阴性供体,缩短肾移植术前血透时间也能减少其发病率.
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| 关 键 词： | 巨细胞病毒性肺炎 肾移植/并发症 病毒感染 |
Multivariate analysis of the risk factors of cytomegalovirus pneumonia after renal transplantation |
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| WEI Qiang,YU Li-xin,DENG Wen-feng,YE Jun-sheng. Multivariate analysis of the risk factors of cytomegalovirus pneumonia after renal transplantation[J]. Journal of Southern Medical University, 2009, 29(6): 1182 |
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| Authors: | WEI Qiang YU Li-xin DENG Wen-feng YE Jun-sheng |
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| Affiliation: | WEI Qiang,YU Li-xin,DENG Wen-feng,YE Jun-sheng Department of Organ Transplantation,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China |
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| Abstract: | Objective To identify the risk factors for cytomegalovirus (CMV) pneumonia after renal transplantation and investigate the early precaution measures. Methods A retrospective study was conducted in a group of 28 patients undergoing renal transplantation who were readmitted because of CMV pneumonia between Jan, 2005 and Dec, 2007. Chi-square test and multivariate logistic regression were used to identity the significant risk factors. Results Seven factors, namely recipient age, acute graft rejection, pre-tran... |
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| Keywords: | cytomegalovirus pneumonia renal transplantation complications viral infection |
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