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Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes,desmoplastic histology and patient survival in human medulloblastomas
Authors:Patrick N. Harter  Peter Baumgarten  Jenny Zinke  Karl Schilling  Stefan Baader  Ann‐Kathrin Hartmetz  Jens Schittenhelm  Rudi Beschorner  Stefan Liebner  Dorothea Schulte  Karl‐Heinz Plate  Paul Gutwein  Andrey Korshunov  Stefan M. Pfister  David T. W. Jones  Kai Doberstein  Michel Mittelbronn
Affiliation:1. Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany;2. German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany;3. Department of Neurosurgery, Goethe University, Frankfurt, Germany;4. Institute for Anatomy, Rheinische‐Friedrich‐Wilhelms University, Bonn, Germany;5. Institute of Pharmacology, Goethe University, Frankfurt, Germany;6. Department of Neuropathology, Eberhardt‐Karls University, Tuebingen, Germany;7. Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany;8. Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany;9. Department of Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany
Abstract:
Keywords:cerebellar development  medulloblastoma  PAX8  SHH  WNT
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