|
|||||
|
|
| 加替沙星与氧氟沙星治疗感染性疾病临床对比 | |
| 引用本文： | 兰天飚,吴笑春,辛华雯,司斌,吴江平,余爱荣. 加替沙星与氧氟沙星治疗感染性疾病临床对比[J]. 医药导报, 2003, 22(9): 621-623 |
| 作者姓名： | 兰天飚 吴笑春 辛华雯 司斌 吴江平 余爱荣 |
| 作者单位： | 广州军区武汉总医院全军临床药理基地,430070 |
| 摘 要： | 目的:评价国产加替沙星片治疗急性细菌感染性疾病的有效性和安全性.方法:50例急性细菌感染性疾病患者随机分为治疗组25例,口服加替沙星片200 mg,bid,对照组25例,口服氧氟沙星片200 mg,bid.疗程均7～14 d.结果:治疗组与对照组痊愈率分别为84.0%与80.0%,有效率96.0%与88.0%,细菌清除率100.0%(20/20)与90.5%(19/21),不良反应发生率20.0%与24.0%,两组各项指标比较均差异无显著性(P＞0.05).结论:加替沙星抗菌谱广,抗菌活性强,能安全有效地用于急性细菌感染性疾病的治疗. |
| 关 键 词： | 加替沙星 氧氟沙星 疾病,细菌感染性 |
| 文章编号： | 1004-0781(2003)09-0621-03 |
| 修稿时间： | 2002-12-31 |
Clinical Evaluation on Gatifloxacin and Ofloxacin in the Treatment of Bacterial Infectious Diseases |
|
| LAN Tian-biao,WU Xiao-chun,XIN Hua-wen,SI-Bin,WU Jiang-ping,YU Ai-rong. Clinical Evaluation on Gatifloxacin and Ofloxacin in the Treatment of Bacterial Infectious Diseases[J]. Herald of Medicine, 2003, 22(9): 621-623 | |
| Authors: | LAN Tian-biao WU Xiao-chun XIN Hua-wen SI-Bin WU Jiang-ping YU Ai-rong |
| Abstract: | Objective:To evaluate the efficacy and safety of gatifloxacin in the treatment of bacterial infectious diseases. Methods:All the patients recruited were randomized into the trial and control groups treated with gatifloxacin and ofloxacin respectively. The regimen for gatifloxacin was 0.2 g oral bid for 7-14 d. The regimen for ofloxacin was 0.2 g oral bid for 7-14 d too. Results:The clinical cure rates in the trial and the control groups were 84.0% vs 80.0%; effective rates were 96.0% vs 88.0%; bacterial eradication rates were 100.0% vs 90.5%. The incidence of adverse reaction in the two groups were 20.0% vs 24.0%. There was no significant difference between two groups( P >0.05). Conclusion:Gatifloxacin is a potent antibiotic agent and can be recommended to treat bacterial infectious diseases. |
| Keywords: | Gatifloxacin Ofloxacin Bacterial infectious diseases |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |
| 点击此处可从《医药导报》浏览原始摘要信息 | |
| 点击此处可从《医药导报》下载全文 | |