Novel streptomycin resistance gene from Mycobacterium fortuitum |
| |
| Authors: | Ramón-García Santiago Otal Isabel Martín Carlos Gómez-Lus Rafael Aínsa José A |
| |
| Affiliation: | Departamento de Microbiología, Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad de Zaragoza, C/ Domingo Miral s/n, 50009-Zaragoza, Spain. |
| |
| Abstract: | We have isolated the aph(3")-Ic gene, encoding an aminoglycoside 3"-O-phosphotransferase [APH(3")-Ic], from a genomic library of an environmental Mycobacterium fortuitum strain, selecting for streptomycin resistance. APH(3")-Ic phosphorylates and inactivates streptomycin. Similar genes have been described in Streptomyces griseus and plasmid RSF1010. It is also present in some M. fortuitum clinical isolates. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
