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Dudrick Research Symposium 2015—Lean Tissue and Protein in Health and Disease
Authors:Carrie P. Earthman PhD  RD   LD  Robert R. Wolfe PhD  Steven B. Heymsfield MD
Affiliation:1. Food Science & Nutrition, University of Minnesota–Twin Cities, St Paul, Minnesota, USA;2. University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA;3. Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
Abstract:The 2015 Dudrick Research Symposium “Lean Tissue and Protein in Health and Disease: Key Targets and Assessment Strategies” was held on February 16, 2015, at Clinical Nutrition Week in Long Beach, California. The Dudrick Symposium honors the many pivotal and innovative contributions to the development and advancement of parenteral nutrition made by Dr Stanley J. Dudrick, physician scientist, academic leader, and a founding member of the American Society for Parenteral and Enteral Nutrition. As the 2014 recipient of the Dudrick award, Dr Carrie Earthman chaired the symposium and was the first of 3 speakers, followed by Dr Robert Wolfe and Dr Steven Heymsfield. The symposium addressed the importance of lean tissue to health and response to disease and injury, as well as the many opportunities and challenges in its assessment at the bedside. Lean tissue assessment is beneficial to clinical care in chronic and acute care clinical settings, given the strong relationship between lean tissue and outcomes, including functional status. Currently available bioimpedance techniques, including the use of bioimpedance parameters, for lean tissue and nutrition status assessment were presented. The connection between protein requirements and lean tissue was discussed, highlighting the maintenance of lean tissue as one of the most important primary end points by which protein requirements can be estimated. The various tracer techniques to establish protein requirements were presented, emphasizing the importance of practical considerations in research protocols aimed to establish protein requirements. Ultrasound and other new and emerging technologies that may be used for lean tissue assessment were discussed, and areas for future research were highlighted.
Keywords:body composition  research and diseases  lean body mass  protein requirements  nutrition assessment  nutrition  tracer techniques  lean tissue  bioimpedance
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