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Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex. |
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| Authors: | T Spies C C Morton S A Nedospasov W Fiers D Pious J L Strominger |
| Abstract: | The human major histocompatibility complex (MHC) includes the closely linked genes for the tumor necrosis factors alpha and beta. Their location is within the chromosomal segment between HLA-DR and HLA-A or centromeric of HLA-DP. This assignment is based on Southern blot analysis of a number of different MHC deletion mutants and is corroborated by chromosome in situ hybridization. |
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