The pap operon of avian pathogenic Escherichia coli strain O1:K1 is located on a novel pathogenicity island |
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| Authors: | Kariyawasam Subhashinie Johnson Timothy J Nolan Lisa K |
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| Affiliation: | Iowa State University, 1802 Elwood Drive, VMRI #2, Ames, IA 50011, USA. |
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| Abstract: | We have identified a 56-kb pathogenicity island (PAI) in avian pathogenic Escherichia coli strain O1:K1 (APEC-O1). This PAI, termed PAI I(APEC-O1), is integrated adjacent to the 3' end of the pheV tRNA gene. It carries putative virulence genes of APEC (pap operon), other E. coli genes (tia and ireA), and a 1.5-kb region unique to APEC-O1. The kps gene cluster required for the biosynthesis of polysialic acid capsule was mapped to a location immediately downstream of this PAI. |
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