| 肺癌干细胞的研究进展 |
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| 引用本文： | 赵汝楠1,阮永华1,马丽菊2. 肺癌干细胞的研究进展[J]. 现代肿瘤医学, 2015, 0(11): 1620-1624. DOI: 10.3969/j.issn.1672-4992.2015.11.44 |
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| 作者姓名： | 赵汝楠1 阮永华1 马丽菊2 |
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| 作者单位： | 1.昆明医科大学基础医学院，云南 昆明 650000；2.昆明医科大学附属第一医院，云南 昆明 650000 |
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| 基金项目： | 国家自然科学基金（编号:81160276）；云南省科技厅-昆明医科大学联合专项基金（编号:2011FB181） |
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| 摘 要： | 肺癌干细胞（lung cancer stem cell,LCSC）是肺组织中一小部分具有自我更新和增殖分化潜能，并具耐药功能的特定细胞群。它与肺癌的发生、进展、转移、耐药关系密切。本文对肺癌干细胞的起源、分选以及所涉及到的相关信号通路和标志物等方面进行综述，为未来肺癌的临床诊断及治疗提供新的思路。
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| 关 键 词： | 肺癌干细胞 标志物 信号通路 |
Research advancement of lung cancer stem cells |
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| Zhao Ru’ nan1,Ruan Yonghua1,Ma Liju2. Research advancement of lung cancer stem cells[J]. Journal of Modern Oncology, 2015, 0(11): 1620-1624. DOI: 10.3969/j.issn.1672-4992.2015.11.44 |
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| Authors: | Zhao Ru’ nan1 Ruan Yonghua1 Ma Liju2 |
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| Affiliation: | 1.Department of Basic Medical,Kunming Medical University，Yunnan Kunming 650000,China;2.The First Affiliated Hospital of Kunming Medical University,Yunnan Kunming 650000,China. |
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| Abstract: | Lung cancer stem cell(LCSC),a small part of the lung tissue which has the ability of self-renewing and the potential of proliferation differentiation，is a specific cell population.It has a very close relationship with lung cancer’s occurring，progressing，transferring，drug resistance，and so on.This paper mainly the origin of lung cancer stem cells，their isolation,identification，related signaling pathways，and markers provide some new methods for the clinical diagnosis and treatment of lung cancer in the future. |
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| Keywords: | lung cancer stem cells(LCSC) marker signaling pathway |
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