| 中晚期宫颈癌腹主动脉旁淋巴结转移治疗的临床研究 |
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| 引用本文： | 韩志红1,田小飞1,韩星梅2,翟振波1,杨雪梅1. 中晚期宫颈癌腹主动脉旁淋巴结转移治疗的临床研究[J]. 现代肿瘤医学, 2015, 0(5): 692-694. DOI: 10.3969/j.issn.1672-4992.2015.05.34 |
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| 作者姓名： | 韩志红1 田小飞1 韩星梅2 翟振波1 杨雪梅1 |
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| 作者单位： | 1.陕西省肿瘤医院妇瘤科，陕西 西安 710061;2.长治市第二人民医院妇产科，山西 长治 046000 |
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| 摘 要： | 目的:研究中晚期（Ⅱb-Ⅲb期）宫颈癌腹主动脉旁淋巴结(PALN)转移采用手术和放疗治疗的疗效。方法:选择中晚期（Ⅱb-Ⅲb期）腹主动脉旁淋巴结转移的宫颈癌患者76例，观察组43例，行腹主动脉旁淋巴结清扫术，术后行同步放化学治疗。对照组33例，行宫颈癌同步放化学治疗。分析与患者3年生存率有关的临床病理因素，探讨影响患者预后的因素。结果:手术分期、病理分级、SCCA水平、局部肿瘤大小、腹主动脉旁淋巴结大小、治疗方法与患者的3年生存率有关。多因素分析表明影响患者生存期的因素是分期、分级、局部肿瘤大小、腹主动脉旁淋巴结大小、治疗方法。结论:中晚期宫颈癌腹主动脉旁淋巴结转移，行腹主动脉旁淋巴结切除并辅以术后延伸放疗联合同期化疗，对于病人治疗有重要意义。
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| 关 键 词： | 中晚期宫颈癌 腹主动脉旁淋巴结转移 预后 |
Treatment of advanced cervical cancer patients with isolated para - aortic lymph node metastases |
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| Han Zhihong1,Tian Xiaofei1,Han Xingmei2,Zhai Zhenbo1,Yang Xuemei1. Treatment of advanced cervical cancer patients with isolated para - aortic lymph node metastases[J]. Journal of Modern Oncology, 2015, 0(5): 692-694. DOI: 10.3969/j.issn.1672-4992.2015.05.34 |
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| Authors: | Han Zhihong1 Tian Xiaofei1 Han Xingmei2 Zhai Zhenbo1 Yang Xuemei1 |
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| Affiliation: | 1Department of Gynecology Oncology，Shaanxi Provincial Tumor Hospital，Shaanxi Xi'an 710061，China;2Department of Gynecology and Obstetrics，the Second Hospital of Changzhi City，Shanxi Changzhi 046000,China. |
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| Abstract: | Objective:To evaluate treatment outcomes of surgery and radiotherapy in advanced cervical cancer patients （Ⅱb-Ⅲb） with isolated para-aortic lymph node（PALN） metastases.Methods:All 76 cervical cancer patients with isolated PALN node metastases were studied.Study group:Forty-three patients received para-aortic lymphadenectomy resection and postoperative chemoradiotherapy.Control group:Thirty-three patients received extended field chemoradiotherapy.The relationship between survival rate and clinical pathological parameters were assessed to explore the factors affecting the prognosis of patients．Results:The 3-year overall survival rate had correlation with tumor stage，histological grade，squamous cell carcinoma antigen（SCC Ag） tumor size，PALN size and treatment（P<0.05).Multivariate analysis showed that tumor stage，histological grade，tumor size and PALN size were the prognostic factors of patients with cervical cancer（P<0.05).Conclusion:In cervical cancer with isolated para-aortic lymphnode metastasis para-aortic lymphadenectomy resection and postoperative chemoradiotherapy is important in treatment. |
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| Keywords: | advanced cervical cancer para-aortic lymph node metastases prognosis |
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