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盐酸戊乙奎醚化与盐酸戊乙奎醚过量的临床观察
引用本文:马玉英,李桂花,牛玉芹,姚明星. 盐酸戊乙奎醚化与盐酸戊乙奎醚过量的临床观察[J]. 临床荟萃, 2010, 25(4): 281-283
作者姓名:马玉英  李桂花  牛玉芹  姚明星
作者单位:石河子大学医学院第一附属医院急诊科,新疆,石河子,832008
摘    要:目的 探讨新型抗胆碱药盐酸戊乙奎醚(长托宁)在急性有机磷农药中毒救治中长托宁化的临床表现,为防止长托宁过量与中毒提供参考.方法 急性有机磷农药中毒61例随机分为长托宁治疗组与阿托品治疗组,观察长托宁化与阿托品化的临床指征.结果 31例应用长托宁表现长托宁化,其中7例表现长托宁过量.长托宁化主要表现为皮肤干燥、呼吸道分泌物明显减少或消失、瞳孔扩大、精神轻度亢奋、胆碱酯酶活力上升20%以上、中毒症状减轻等,无心跳加快及心动过速.长托宁过量表现为精神亢奋、幻视幻听、抓空摸空、坐卧不宁、蹂狂型精神症状等,且持续时间较长.结论 长托宁救治急性有机鳞农药中毒应尽快使患者达"长托宁化".长托宁应用不当会发生过量与中毒表现,长托宁过量主要表现为可逆性精神症状,及时停药,作好自伤与他伤的防护,预后较佳.

关 键 词:肺疾病  慢性阻塞性  低氧血症  呼吸  人工  

Clinical observation between penehyclidinezation and excessive use of penehyclidine
MA Yu-ying,LI Gui-hua,NIU Yu-qin,YAO Ming-xing. Clinical observation between penehyclidinezation and excessive use of penehyclidine[J]. Clinical Focus, 2010, 25(4): 281-283
Authors:MA Yu-ying  LI Gui-hua  NIU Yu-qin  YAO Ming-xing
Affiliation:MA Yu-ying,LI Gui-hua,NIU Yu-qin,YAO Ming-xing Department of Emergency,the First Affiliated Hospital,Medical College of Shihezi University,Shihezi 832008,China
Abstract:Objective To observe the clinical performance of penehyclidinezation through the new anticholinergic drug-penehyclidine in the treatment of acute organophosphorus pesticide poisoning,instructive ideas of preventing the excessive use and poisoning of penehyclidine would be provided.Methods Sixty-one patients with acute organophosphorus pesticide were randomly divided into penehyclidine group and atropine group.The clinical indications were studied between penehyclidinezation and excessive use in penehyclidin...
Keywords:poisoning  organophosphorus  penehyclidine  atropine  
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