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前纵隔淋巴瘤与胸腺癌能谱CT的表现差异
引用本文:马拓,曹立秀,李会菊,任红亮,陈大鹏,高媛,李志东,赵新斌,董思圻. 前纵隔淋巴瘤与胸腺癌能谱CT的表现差异[J]. 中国医学科学院学报, 2020, 42(4): 431-435. DOI: 10.3881/j.issn.1000-503X.11708
作者姓名:马拓  曹立秀  李会菊  任红亮  陈大鹏  高媛  李志东  赵新斌  董思圻
作者单位:1.华北理工大学附属医院CT室,河北唐山 063000;2.唐山市人民医院CT室,河北唐山 063000;3.华北理工大学中医学院,河北唐山 063000
基金项目:2019年度河北医学科学研究重点课题计划(20191622)
摘    要:目的探讨前纵隔淋巴瘤与胸腺癌能谱CT的表现差异。方法选取唐山市人民医院穿刺活检病理证实的前纵隔淋巴瘤22例和胸腺癌28例,经能谱CT进行平扫和增强检查,应用能谱分析软件测量不同单能量下的CT值及病变部位的碘含量、水含量变化,比较前纵隔淋巴瘤和胸腺癌的差异。结果胸腺癌动脉期和静脉期40~80 keV单能量CT值高于前纵隔淋巴瘤,差异有统计学意义(P=0.001,P=0.037,P=0.042,P=0.034,P=0.002;P=0.016,P=0.013,P=0.018,P=0.024,P=0.012);胸腺癌在90~110 keV单能量CT值与前纵隔淋巴瘤比较差异均无统计学意义(P均>0.05)。胸腺癌动脉期和静脉期水浓度低于前纵隔淋巴瘤,差异有统计学意义(P=0.030,P=0.037);碘浓度高于前纵隔淋巴瘤,差异有统计学意义(P=0.026,P=0.000)。结论前纵隔淋巴瘤与胸腺癌在能谱CT检查40~80 keV单能量CT值及动脉期和静脉期水浓度、碘浓度上的差异显著,并可以此区分两者。

关 键 词:前纵隔  淋巴瘤  胸腺癌  体层摄影术
收稿时间:2019-06-27

Different Energy Spectrum CT Findings between Anterior Mediastinal Lymphoma and Thymic Carcinoma
MA Tuo,CAO Lixiu,LI Huiju,REN Hongliang,CHEN Dapeng,GAO Yuan,LI Zhidong,ZHAO Xinbin,DONG Siqi. Different Energy Spectrum CT Findings between Anterior Mediastinal Lymphoma and Thymic Carcinoma[J]. Acta Academiae Medicinae Sinicae, 2020, 42(4): 431-435. DOI: 10.3881/j.issn.1000-503X.11708
Authors:MA Tuo  CAO Lixiu  LI Huiju  REN Hongliang  CHEN Dapeng  GAO Yuan  LI Zhidong  ZHAO Xinbin  DONG Siqi
Affiliation:1.CT Room,Affiliated Hospital of North China University of Science and Technology,Tangshan,Hebei 063000,China;2.CT Room,Tangshan People’s Hospital,Tangshan,Hebei 063000,China;3.College of Traditional Chinese Medicine,North China University of Science and Technology,Tangshan,Hebei 063000,China
Abstract:Objective To investigate the differences in energy spectrum CT findings between anterior mediastinal lymphoma and thymic carcinoma. Methods Twenty-two cases of anterior mediastinal lymphoma and 28 cases of thymic carcinoma confirmed by biopsy in Tangshan People’s Hospital were selected.The CT values and changes of iodine content and water content in lesion sites were measured by energy spectrum analysis software.The differences between anterior mediastinal lymphoma and thymic carcinoma were compared. Results The single-energy CT value of 40-80 keV in thymus carcinoma was higher than that in anterior mediastinal lymphoma(P=0.001,P=0.037,P=0.042,P=0.034,P=0.002;P=0.016,P=0.013,P=0.018,P=0.024,P=0.012).The difference in the single-energy CT value of 90-110 keV between anterior mediastinal lymphoma and thymic carcinoma showed no statistical significance(all P>0.05).The concentrations of water in the arterial and venous stages of thymic carcinoma were significantly lower than those in the anterior mediastinal lymphoma(P=0.030,P=0.037),whereas the iodine concentrations were significantly higher(P=0.026,P=0.000). Conclusion Anterior mediastinal lymphoma and thymic carcinoma have remarkably different 40-80 keV single energy CT value and iodine concentration in arterial and venous phases,which may be helpful for the differential diagnosis of these two malignancies.
Keywords:anterior mediastinal  lymphoma  thymic carcinoma  tomography  
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