| 骨髓间充质干细胞在口腔医学中的应用 |
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| 引用本文： | 杨镕羽,宋飞,黄浩,段开文,向盈盈. 骨髓间充质干细胞在口腔医学中的应用[J]. 昆明医科大学学报, 2023, 44(3): 155-159. DOI: 10.12259/j.issn.2095-610X.S20230323 |
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| 作者姓名： | 杨镕羽 宋飞 黄浩 段开文 向盈盈 |
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| 作者单位： | 1.昆明医科大学附属延安医院口腔科，云南 昆明 650031 |
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| 基金项目： | 国家自然科学基金资助项目（31860147）；昆明市卫生健康委员会卫生科研课题（2022-08-01-004） |
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| 摘 要： | 在颌面部，由肿瘤、创伤、先天或后天性的急性引起的组织缺损使患者的容貌、正常生理功能及心理健康受到严重伤害，使患者的整体生活质量下降。寻找适当的治疗方法来恢复这些缺损的组织是至关重要的。近年来，随着组织工程的飞速发展，人们对于口腔组织再生技术十分重视。骨髓来源的间充质干细胞（bone marrow mesenchymal stem cells,BMSCs）由于其具有向其他细胞分化的潜力，最常被应用于再生医学。近年来，研究人员开发了许多基于BMSCs的生物支架材料，利用其卓越的性能以满足口腔颌面组织工程的需求。综述BMSCs在口腔医学的研究进展及应用，探讨其在口腔医学中的应用前景。
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| 关 键 词： | 骨髓间充质干细胞 组织工程 细胞疗法 |
| 收稿时间： | 2022-08-16 |
Application of Bone Marrow Mesenchymal Stem Cells in Stomatology |
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| Affiliation: | 1.Dept. of Stomatology，Yan’an Hospital of Kunming，Kunming Yunnan 6500312.Dept. of Minimally Invasive Intervention ，The 3rd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650106，China |
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| Abstract: | In the maxillofacial region, tissue defects caused by tumors, trauma, congenital or acquired acute can cause serious damage to the patient’s appearance, normal physiological function and mental health, and overall quality of life of the patient. It is very important to find an appropriate treatment method to restore these defective tissues. In recent years, with the rapid development of tissue engineering, people attach great importance to oral tissue regeneration technology. Bone marrow mesenchymal stem cells （BMSCs）are most often used in regenerative medicine because of their potential to differentiate into other cells. In recent years, researchers have developed many biological scaffolds based on BMSCs to meet the needs of oral and maxillofacial tissue engineering with their excellent performance. This review introduces the research progress and application of BMSCs in stomatology, and discusses its application prospect in stomatology. |
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