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低浓度苯作业工人健康状况及影响因素分析
引用本文:张静, 吕建萍, 张晨, 周莉芳, 叶云杰, 孙品, 程周祥, 夏昭林. 低浓度苯作业工人健康状况及影响因素分析[J]. 中国公共卫生, 2012, 28(8): 1020-1022. DOI: 10.11847/zgggws2012-28-08-04
作者姓名:张静  吕建萍  张晨  周莉芳  叶云杰  孙品  程周祥  夏昭林
作者单位:1.新疆医科大学附属肿瘤医院科研科, 新疆 乌鲁木齐 830011;2.复旦大学公共卫生学院劳动卫生教研室;3.芜湖市疾病预防控制中心;4.新疆医科大学公共卫生学院毒理学教研室
摘    要:
目的 探讨低浓度苯接触工人的健康状况及影响因素.方法 对823名研究对象(直接接苯组253人,间接接苯组482人,对照组88人)进行健康体检,采用χ2检验比较各组卫生习惯、临床症状及白细胞降低率差异,采用logistic回归分析白细胞降低的影响因素.结果 直接接苯组经常使用防护用品人数的比例(78.3%)明显高于间接接苯组(55.2%)(P<0.05);间接接苯组和直接接苯组白细胞波动率(32.2%,40.7%)及白细胞降低率(20.5%,27.7%)均高于对照组(6.8%,0),差异有统计学意义(P<0.05);苯暴露、年龄和接苯工龄是白细胞降低的影响因素.结论 低浓度苯接触仍可能会产生血液毒性,白细胞计数是监测低浓度苯接触血液毒性的一个敏感指标.

关 键 词:  低浓度暴露  白细胞降低  血液毒性
收稿时间:2011-08-08

Health status and its risk factors among workers with low level benzene exposure
ZHANG Jing, LÜ Jian-ping, ZHANG Chen, . Health status and its risk factors among workers with lowlevel benzene exposure[J]. Chinese Journal of Public Health, 2012, 28(8): 1020-1022. DOI: 10.11847/zgggws2012-28-08-04
Authors:ZHANG Jing,LÜ   Jian-ping,ZHANG Chen
Affiliation:1.Department of Scientific Research, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region 830011, China
Abstract:
Objective To examine health status of the workers with low level benzene exposure and to explore its risk factors.Methods The health habit,clinical symptoms,and the decreased rate of white blood cell(WBC) were detected and compared among 823 health examinees(including 253 with direct benzene exposure,482 with indirect benzene exposure workers,and 88 without benzene exposure) using χ2 test.Risk factor analysis was conducted using logistic regression model.Results The workers with direct benzene exposure had a significantly higher rate of using personal protective equipment(78.3%) than those with indirect benzene exposuse(55.2%)(P<0.05).Both workers with direct and inderect benzene exposure had a higher WBC fluctuation rate(32.2% and 40.7%) and a leukocytopenia rate(20.5% and 27.7%) than unexposed controls(6.8%,0%)(P<0.05).Benzene exposure,age,and the years with benzene exposuue were the risk factors of leukocytopenia.Conclusion Low level benzene exposure could lead to hematotoxicity and leukocytopenia might be a susceptible predictor of hematotoxicity among the workers with benzene exposure.
Keywords:benzene  low level exposure  leukocytopenia  hematotoxicity
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