In vitro activities of ravuconazole and four other antifungal agents against fluconazole-resistant or -susceptible clinical yeast isolates |
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| Authors: | Cuenca-Estrella Manuel Gomez-Lopez Alicia Mellado Emilia Garcia-Effron Guillermo Rodriguez-Tudela Juan L |
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| Affiliation: | Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda (Madrid), Spain. mcuenca-estrella@isciii.es |
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| Abstract: | The activities of ravuconazole and four other antifungal agents were tested against a collection of 1,796 clinical yeast isolates, including fluconazole-susceptible and -resistant strains. Ravuconazole was active against the majority of fluconazole-resistant isolates; but for 102 of 562 (18%) resistant isolates, mainly Candida tropicalis, Candida glabrata, and Cryptococcus neoformans, ravuconazole MICs were > or =1 microg/ml. |
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