| 持续脑功能监测在新生儿缺氧缺血性脑病的应用效果 |
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| 引用本文： | 陈莉,陈信. 持续脑功能监测在新生儿缺氧缺血性脑病的应用效果[J]. 中华全科医学, 2020, 18(4): 564-567. DOI: 10.16766/j.cnki.issn.1674-4152.001299 |
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| 作者姓名： | 陈莉 陈信 |
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| 作者单位： | 1. 蚌埠医学院第一附属医院儿科, 安徽 蚌埠 233004; |
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| 基金项目： | 安徽省高校自然科学研究重点项目(KJ2019A0378)蚌埠市级科技创新指导类项目(20180308)安徽省高等学校省级质量工程项目(2018jyxm0815)蚌埠市社会科学规划项目(BB19D005) |
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| 摘 要： | 目的 缺氧缺血性脑病的新生儿需做早期诊断,本次研究即对持续脑功能监测的应用效果进行观察。 方法 本次研究对象均为2018年6月—2019年5月于蚌埠医学院第一附属医院确诊为缺氧缺血性脑病的新生儿,依据随机数字表法将研究对象分为对照组、观察组,每组30例,观察组应用持续脑功能监测,对照组应用经颅多普勒超声(TCD)监测,对2组的应用效果进行比较。 结果 2组敏感性、特异性比较,观察组分别为90.00%、86.67%,对照组分别为63.33%、60.00%,观察组明显高于对照组,差异有统计学意义(均P<0.05);2组脑功能比较,差异无统计学意义(P>0.05);随着时间的延长,2组缺氧缺血性脑病新生儿的Vs和Vd均有不同程度地提高,与对照组比较,观察组24 h和48 h的Vs和Vd检测值均明显降低(均P<0.05),2组72 h的Vs和Vd差异无统计学意义(均P>0.05),2组不同时间的RI差异无统计学意义(P>0.05),各参数组间与时间不存在交互作用(P>0.05)。 结论 对于新生儿缺氧缺血性脑病患者进行监护,持续脑功能监测是一种客观、可靠的脑功能监护手段,可提高监护的准确性,准确反应病情,利于后期的治疗,有利于对新生儿生命安全的保障。
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| 关 键 词： | 缺氧缺血性脑病 持续脑功能监测 早期诊断 |
| 收稿时间： | 2019-07-01 |
Effect of continuous brain function monitoring on neonatal hypoxic-ischemic encephalopathy |
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| Affiliation: | Department of Pediatrics, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China |
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| Abstract: | Objective To observe the application effect of continuous brain function monitoring in early diagnosis of neonatal hypoxic-ischemic encephalopathy. Methods Total 60 neonates with hypoxic-ischemic encephalopathy diagnosed in our hospital from June 2018 to May 2019 were selected in this study. They were divided into control group and observation group with 30 cases in each group. Continuous brain function monitoring was used in the observation group, and Transcranial Doppler(TCD) monitoring was used in the control group. The application effect of the two groups was compared. Results The sensitivity and specificity of the two groups were 90.00% and 86.67% in the observation group, 63.33% and 60.00% in the control group, respectively(all P<0.05). The difference of the brain function between the two groups was not statistically significant(P>0.05). The Vs and Vd of the neonates with hypoxic-ischemic encephalopathy increased in a way of time dependent way. Compared with the control group, the Vs and Vd of the observation group at 24 h and 48 h were significantly reduced(all P<0.05). There was no significant difference in Vs and Vd between 2 groups at 72 h(all P>0.05), and there was no significant difference in RI between 2 groups at different times(P>0.05). There was no interaction between the parameter groups and time(P>0.05). Conclusion Continuous brain function monitoring is an objective and reliable method for the monitoring of neonatal hypoxic-ischemic encephalopathy, which can improve the accuracy of monitoring, accurately reflect the state of illness, facilitate the later treatment and guarantee the life safety of the newborn. |
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