In vitro synergistic cytoreductive effects of zoledronic acid and radiation on breast cancer cells |
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| Authors: | A Ugur Ural Ferit Avcu Muhammed Candir Metin Guden M Ali Ozcan |
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| Affiliation: | (1) Department of Hematology, Gulhane Military Medical Faculty, Ankara, Turkey;(2) Department of Medical and Cancer Research Center, Gulhane Military Medical Faculty, Ankara, Turkey;(3) Department of Internal Medicine, Gulhane Military Medical Faculty, Ankara, Turkey;(4) Department of Radiation Oncology, Gulhane Military Medical Faculty, Ankara, Turkey;(5) Department of Hematology, Medical Faculty of Dokuz Eylul University, Izmir, Turkey |
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| Abstract: | Introduction Bisphosphonates are mostly used in the treatment of bone metastases. They have been shown to act synergistically with other chemotherapeutic agents. It is not known, however, whether similar synergistic effects exist with radiation on breast cancer cells. |
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