| 多孔纳米羟基磷灰石/聚酰胺复合骨修复材料的制备 |
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| 引用本文： | 强巴单增,刘晓兰. 多孔纳米羟基磷灰石/聚酰胺复合骨修复材料的制备[J]. 中国组织工程研究, 2016, 20(3): 392-396. DOI: 10.3969/j.issn.2095-4344.2016.03.016 |
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| 作者姓名： | 强巴单增 刘晓兰 |
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| 作者单位： | 西藏大学，西藏自治区拉萨市 850002；南方医科大学珠江医院骨科中心，广东省广州市 510280 |
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| 基金项目： | 广东省自然科学基金(7005191) |
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| 摘 要： |
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| 关 键 词： | 生物材料 纳米材料 多孔纳米羟基磷灰石 聚酰胺 复合骨修复材料 发泡剂 制备方法 性能 广东省自然科学基金 |
| 收稿时间： | 2015-11-05 |
Preparation of porous nano-hydroxyapatite/polyamide composites for bone repair |
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| Qiangbashanzeng,Liu Xiao-lan. Preparation of porous nano-hydroxyapatite/polyamide composites for bone repair[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(3): 392-396. DOI: 10.3969/j.issn.2095-4344.2016.03.016 |
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| Authors: | Qiangbashanzeng Liu Xiao-lan |
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| Affiliation: | Tibet University, Lhasa 850002, Tibet Autonomous Region, China; Department of Orthopedics, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China |
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| Abstract: | BACKGROUND: Compared with dense bone repair materials, porous materials has lower intensity, but its three-dimensional porous network structure can ensure a larger surface area that is more conducive to cell adhesion, growth and division as well as nutrient transmission.OBJECTIVE: To investigate the preparation and performance of porous nano-hydroxyapatite/polyamide composites.METHODS: Porous nano-hydroxyapatite/polyamide composites were prepared using chemical foaming method, and different composite bone repair materials were made by regulating foaming agent amount and nano-hydroxyapatite content. Mechanical properties, porosity and composition of the composite bone repair materials were detected.RESULTS AND CONCLUSION: Porous nano-hydroxyapatite/polyamide composites were substantially tubular channels, and had relatively good connectivity and uniform distribution, with a pore size of 260-400 μm, porosity of 35%-57%. Foaming agent amount, nano-hydroxyapatite content and density of composite materials all are influential factors of the total porosity. Porous nano-hydroxyapatite/polyamide composites have better mechanical properties and compressive strength than the cancellous bone, and the foaming agent has no influence on its shape, composition and diffraction peaks. |
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