CELLS INVOLVED IN THE IMMUNE RESPONSE : XVI. THE RESPONSE OF IMMUNE RABBIT CELLS TO PHYTOHEMAGGLUTININ, ANTIGEN, AND GOAT ANTI-RABBIT IMMUNOGLOBULIN ANTISERUM |
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Authors: | Fritz Daguillard and Maxwell Richter |
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Affiliation: | From The Harry Webster Thorp Laboratories, Division of Immunochemistry and Allergy, McGill University Clinic, Royal Victoria Hospital, Montreal, Quebec, Canada |
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Abstract: | There exists in the rabbit a population of lymphocytes carrying immunoglobulin-like receptors on their surface. These receptors interact with antigen and with anti-immunoglobulin antibodies and appear to mediate the recognition process leading to the humoral immune response. There exists in the rabbit a second population of lymphocytes capable of reacting with phytohemagglutinin. This population of lymphocytes is different from the one capable of reacting with soluble protein antigens or anti-immunoglobulin antiserum and is probably involved in the mediation of cellular immunity. |
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