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| 广东珠三角地区女性宫颈液基细胞学检查结果分析 | |
| 引用本文： | 吴心音;黄民主;李洪波;郑宝文;朱庆义. 广东珠三角地区女性宫颈液基细胞学检查结果分析[J]. 广东医学, 2008, 29(12) |
| 作者姓名： | 吴心音 黄民主 李洪波 郑宝文 朱庆义 |
| 作者单位： | 中南大学湘雅公共卫生学院 中南大学公共卫生学院硕士生导师 广州金域医学检验中心 |
| 摘 要： | 目的 了解最近5年广东省珠三角地区宫颈病变女性的年龄、地区和时间分布情况，为开展系统的宫颈细胞学筛查计划提供基线资料。 方法 对珠三角地区最近5年宫颈液基细胞学送检样本采用Thinprep液基细胞学检测(TCT)和the Bethesda system (TBS)分级系统诊断，以Atypical squamous/ glandular Cells (ASC/AGC)及以上级别病变为细胞学阳性，用SPSS13.0建立数据库，用频率对计数资料进行统计描述，假设检验用χ2检验；用均数和标准差描述计量资料，统计推断用方差分析。 结果 共检测345 499份送检样本，总阳性检出率为7.72%，年龄在10 ~92岁之间，平均为(32.46±8.43)岁。不同地区和不同年份送检样本的阳性检出率差异均有统计学意义(P<0.05)。 结论 广东省珠三角地区女性宫颈细胞学检查阳性检出率较高。TCT是一种灵敏度相对较高的宫颈细胞学筛查方法，利用该法开展系统的宫颈细胞学筛查，对于保护当地女性的健康具有重要的临床价值和流行病学意义，并为全国宫颈细胞学筛查的开展提供了科学依据。 |
| 关 键 词： | 宫颈病变 液基细胞学(TCT) 宫颈癌筛查 广东省珠三角 |
A Analysis of Female Cervical Liquid-based Cytology Test Results in Guang-dong Province Pearl River Delta Region |
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| Abstract: | Objective Investigate the age, region and time distribution of female with cervical lesion in Guangdong Province Pearl River Delta(PRD) last 5 years. To provide baseline information for cervical cytology screening plans in Guangdong PRD region. Methods The cervical cytology samples submitted from PRD region last 5 years were detected with Thinprep liquid-based cytology test(TCT) and the Bethesda system(TBS). The samples of ASC/AGC or more abnormal cell were postive. Use SPSS13.0 build up a database, Numeration data were desribed as frequency and statistical test with χ2 test, and measurement data were reported with mean and standard deviation, and were analyzed with analysis of variance. Results 345499 cases of TCT samples was detected. The overall positive rate was 7.72%, 345,499 examined cases age distribution was between 10-year-old and to 92-year-old, with an average age of 32.46 ± 8.43 years. All cases were from seven regions of Pearl River Delta region in Guangdong Province, which are Guangzhou, Shenzhe, Dongguan, Foshan, Huizhou, Zhongshan and Jiangmen a total of seven cities. The positive rate of different regions and different years had a significant difference (P<0.05). Conclusion The cervical cytology positive rate in Guangdong Province PRD region was high. As a cervical cytology screening methods, the sensitivity of TCT was comparatively high, systemic cervical cytology screening program could be carried out with TCT to protect the health of local women, which has an important clinicl value and epidemiological significance, and provide scientific evidence for the national cervical cytology screening program. |
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