| 柴胡桂枝汤联合盐酸羟考酮缓释片治疗癌性疼痛的临床疗效观察 |
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| 引用本文： | 江 恒1,原薇薇2,廖 皓1,王 奎1,李 莉1,王跃蓉1,代洪玉1,袁 滢1,孙 薏1. 柴胡桂枝汤联合盐酸羟考酮缓释片治疗癌性疼痛的临床疗效观察[J]. 现代肿瘤医学, 2020, 0(14): 2517-2519. DOI: 10.3969/j.issn.1672-4992.2020.14.034 |
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| 作者姓名： | 江 恒1 原薇薇2 廖 皓1 王 奎1 李 莉1 王跃蓉1 代洪玉1 袁 滢1 孙 薏1 |
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| 作者单位： | 1.西部战区空军医院肿瘤科，四川 成都 610021;2.西部战区总医院肿瘤科，四川 成都 610083 |
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| 摘 要： | 目的:探讨柴胡桂枝汤联合盐酸羟考酮缓释片治疗癌性疼痛的疗效。方法:80例癌痛患者随机分为对照组和治疗组各40例，参照癌痛规范化疗治疗要求，观察患者生活质量评分改善、不良反应、日均吗啡消耗量、爆发痛频次等指标。结果:治疗组便秘发生率（5.0% vs 22.5%）、总不良反应发生率（47.5% vs 85.0%）均显著低于对照组（P＜0.05）；治疗组生活质量评分改善［（22.25±6.60）分］显著高于对照组［（17.00±6.07）分］（P＜0.05）；治疗组日均吗啡消耗量［（203.82±52.58）mg］显著低于对照组［(245.09±67.57) mg］(P＜0.05)；治疗组累积爆发痛频次（10.58±1.80）显著低于对照组（13.55±2.58）（P＜0.05）。结论:柴胡桂枝汤联合盐酸羟考酮缓释片治疗癌痛具有增效减毒之效，更能提高癌痛患者生活质量。
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| 关 键 词： | 癌性疼痛 柴胡桂枝汤 盐酸羟考酮缓释片 |
Clinical observation of Chai Hu Gui Zhi decoction in treating cancer pain combined with oxycodone hydrochloride sustained release tablets |
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| Jiang Heng1,Yuan Weiwei2,Liao Hao1,Wang Kui1,Li Li1,Wang Yuerong1,Dai Hongyu1,Yuan Ying1,Sun Yi1. Clinical observation of Chai Hu Gui Zhi decoction in treating cancer pain combined with oxycodone hydrochloride sustained release tablets[J]. Journal of Modern Oncology, 2020, 0(14): 2517-2519. DOI: 10.3969/j.issn.1672-4992.2020.14.034 |
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| Authors: | Jiang Heng1 Yuan Weiwei2 Liao Hao1 Wang Kui1 Li Li1 Wang Yuerong1 Dai Hongyu1 Yuan Ying1 Sun Yi1 |
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| Affiliation: | 1.Department of Oncology,Western Theater Command Air Force Hospital of PLA,Sichuan Chengdu 610021,China;2.Center of Oncology，Western Theater Command General Hospital of PLA，Sichuan Chengdu 610083,China. |
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| Abstract: | Objective:To study the clinical effection of Chai Hu Gui Zhi decoction in treating cancerous pain combined with oxycodone hydrochloride sustained release tablets.Methods:80 patients with cancerous pain were randomly divided into the control group(n=40) and the treating group(n=40).In accordance with standardized treatment of cancer pain,quality of life scores,adverse reactions,average daily caffeine consumption,frequency of breakthough pain were observed.Results:Incidence of constipation and incidence of total adverse reaction in the treatment group were significantly lower than in the control group（5.0% vs 22.5%,47.5% vs 85.0%,P＜0.05）.Changed quality of life scores in the treatment group were siginificantly higher than in the control group（22.25±6.60 vs 17.00±6.07,P＜0.05）.Average daily caffeine consumption and frequency of breakthough pain in the treatment group were significantly lower than in the control group［（203.82±52.58）mg vs （245.09±67.57）mg,10.58±1.80 vs 13.55±2.58,P＜0.05］.Conclusion:Chai Hu Gui Zhi decoction combined with oxycodone hydrochloride sustained-release tablets in the treatment of cancer pain is synergistic attenuated effect,can improve the quality of life of patients with cancer pain. |
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| Keywords: | cancer pain Chai Hu Gui Zhi decoction oxycodone hydrochloride sustained-release tablets |
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