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Blood pressure control and cardiovascular risk in hypertensive patients with type 2 diabetes: The German T2Target registry
Authors:Thomas Mengden MD  Uwe Ligges PhD  Johanna Mielke  Peter Bramlage MD  Andrea Korzinek  Walter Sehnert MD
Affiliation:1. Kerckhoff Clinic, Rehabilitation, ESH Excellence Centre, Bad Nauheim, Germany;2. TU Dortmund University, Dortmund, Germany;3. Institute for Pharmacology and Preventive Medicine, Cloppenburg, Germany;4. Servier Deutschland GmbH, München, Germany;5. Clinical Research Institute, Dortmund, Germany
Abstract:Blood pressure control in patients with type 2 diabetes and hypertension is poor. It is unclear how effectively general practitioners assess and treat such patients. T2Target included hypertensive patients with type 2 diabetes mellitus who had undergone ambulatory blood pressure monitoring within the past 3 months. Recordings were analyzed by the general practitioner and an independent center and the conclusions were compared. Nighttime hypertension was reported less frequently by the general practitioner in comparison with central assessment (43.9% vs 77.9%, P<.001), as were masked (4.0% vs 13.1%, P<.001) and isolated office (4.4% vs 8.8%, P<.001) hypertension. A total of 13.9% of patients were deemed to have controlled blood pressure (ambulatory blood pressure monitoring). For the 784 patients with uncontrolled blood pressure, 40.7% underwent no change to their antihypertensive treatment. Cardiovascular risk was underestimated, with 11.1% deemed to be at very high risk, in contrast to the 97.0% of patients by central assessment. In conclusion, blood pressure control in hypertensive patients with type 2 diabetes mellitus is poor and not accurately assessed by office‐based general practitioners, despite the use of ambulatory blood pressure monitoring.
Keywords:ambulatory  antihypertensive drugs  cardiovascular risk  comorbidities  diabetes  masked  white coat
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