| 角膜内皮炎药物治疗后内皮细胞的观察 |
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| 引用本文： | 陈凯,张玉光,韩旭光,徐湘辉,丁刚. 角膜内皮炎药物治疗后内皮细胞的观察[J]. 山东大学耳鼻喉眼学报, 2013, 27(6): 82-84. DOI: 10.6040/j.issn.1673-3770.0.2013.239 |
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| 作者姓名： | 陈凯 张玉光 韩旭光 徐湘辉 丁刚 |
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| 作者单位： | 1.莱芜钢铁集团有限公司医院眼科， 山东 莱芜 271100； 2.济南市第二人民医院眼科， 济南 250001 |
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| 摘 要： | 目的 探讨角膜内皮炎对角膜内皮细胞数量和形态的影响。方法 选择角膜内皮炎患者20例(20眼)，其中盘状型13例,弥漫型7例。入院后常规给予抗病毒药物及皮质类固醇激素眼水。应用角膜内皮镜于治愈后4~6周观察角膜内皮细胞的密度、六边形细胞的比例及变异系数的变化，并以健眼为对照组。结果 治疗组角膜内皮细胞的密度较对照组明显降低，六边形细胞所占的比例降低，而变异系数增加；弥漫型内皮炎组与盘状型内皮炎组比较，细胞密度降低，六边形细胞所占的比例降低，变异系数增加。结论 角膜内皮炎对角膜内皮细胞造成损害，导致明显的内皮细胞数量和形态改变，不同分型之间存在区别。
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| 关 键 词： | 治疗 角膜内皮镜 角膜内皮炎 |
| 收稿时间： | 2013-08-14 |
Observation of the endothelial cells of corneal endotheliitis after treatment |
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| CHEN Kai,ZHANG Yu-guang,HAN Xu-guang,XU Xiang-hui,DING Gang. Observation of the endothelial cells of corneal endotheliitis after treatment[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2013, 27(6): 82-84. DOI: 10.6040/j.issn.1673-3770.0.2013.239 |
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| Authors: | CHEN Kai ZHANG Yu-guang HAN Xu-guang XU Xiang-hui DING Gang |
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| Affiliation: | 1. Department of Ophthalmology, Laiwu Steel Group Hospital, Laiwu 271100, Shandong, China; 2. Department of Ophthalmology, Jinan Second People′s Hospital, Jinan 250001, China |
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| Abstract: | Objective To investigate the effect of corneal endotheliitis on the number and morphology of corneal endothelial cells. Methods The study group included 20 cases (20eyes), including 13 cases of disciform endotheliitis and 7 cases of diffuse endotheliitis. All patients accepted systemic and topical antiviral medications combined with corticosteroids. The endothelium cells checked by corneal endothelial microscope were analyzed for cell density, coefficient variation of cell size and hexgonality 4-6 weeks after the patients were cured. The healthy eyes were set as the control group. Results Compared with the control group, the treatment group had lower corneal endothelial cell density and hexagonal cell ratio and higher variation coefficient. Compared with the disciform endotheliitis group, the diffuse endotheliitis group had lower corneal endothelial cell density and hexagonal cell ratio and higher variation coefficient. Conclusion Corneal endotheliitis can damage the corneal endothelial cells, leading to significant changes in their number and morphology. There were distinctions between different types. |
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| Keywords: | Corneal endotheliitis Treatment Corneal endothelial microscope |
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